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  1. Content type: Research article

    Recently, a new algorithm for automatic computer certification of verbal autopsy data named InSilicoVA was published. The authors presented their algorithm as a statistical method and assessed its performance ...

    Authors: Abraham D. Flaxman, Jonathan C. Joseph, Christopher J. L. Murray, Ian Douglas Riley and Alan D. Lopez

    Citation: BMC Medicine 2018 16:56

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  2. Content type: Research article

    Ethnic minority service users with schizophrenia and schizoaffective disorders may experience inequalities in care. There have been no recent studies assessing access to evidence-based treatments for psychosis...

    Authors: Jayati Das-Munshi, Dinesh Bhugra and Mike J. Crawford

    Citation: BMC Medicine 2018 16:55

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  3. Content type: Research article

    Autonomic dysreflexia is a severe and potentially life-threatening condition in patients with spinal cord injury, as it can lead to myocardial ischemia, brain hemorrhage, or even death. Urodynamic investigatio...

    Authors: Matthias Walter, Stephanie C. Knüpfer, Jacquelyn J. Cragg, Lorenz Leitner, Marc P. Schneider, Ulrich Mehnert, Andrei V. Krassioukov, Martin Schubert, Armin Curt and Thomas M. Kessler

    Citation: BMC Medicine 2018 16:53

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  4. Content type: Research article

    Gold mines represent a potential hotspot for Mycobacterium tuberculosis (Mtb) transmission and may be exacerbating the tuberculosis (TB) epidemic in South Africa. However, the presence of multiple factors complic...

    Authors: Stewart T. Chang, Violet N. Chihota, Katherine L. Fielding, Alison D. Grant, Rein M. Houben, Richard G. White, Gavin J. Churchyard, Philip A. Eckhoff and Bradley G. Wagner

    Citation: BMC Medicine 2018 16:52

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  5. Content type: Correspondence

    Despite the gender parity existing in medical schools for over three decades, women remain underrepresented in academic medical centers, particularly in senior ranks and in leadership roles. This has consequen...

    Authors: Reena Pattani, Christine Marquez, Camellia Dinyarian, Malika Sharma, Julie Bain, Julia E. Moore and Sharon E. Straus

    Citation: BMC Medicine 2018 16:48

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  6. Content type: Research article

    While the heterogeniety of pain progression has been studied in chronic diseases, the extent to which patterns of pain progression among people in general as well as across different diseases affect social, ci...

    Authors: Richard J. E. James, David A. Walsh and Eamonn Ferguson

    Citation: BMC Medicine 2018 16:51

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  7. Content type: Research article

    Meat is an important source of high-quality protein and vitamin B but also has a relatively high content of saturated and trans fatty acids. Although protein and vitamin B intake seems to protect people from func...

    Authors: Ellen A. Struijk, José R. Banegas, Fernando Rodríguez-Artalejo and Esther Lopez-Garcia

    Citation: BMC Medicine 2018 16:50

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  8. Content type: Research article

    In November 2016, the Dutch Health Council recommended hepatitis B (HBV) screening for first-generation immigrants from HBV endemic countries. However, these communities show relatively low attendance rates fo...

    Authors: Nora Hamdiui, Mart L. Stein, Aura Timen, Danielle Timmermans, Albert Wong, Maria E. T. C. van den Muijsenbergh and Jim E. van Steenbergen

    Citation: BMC Medicine 2018 16:47

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  9. Content type: Research article

    Drug-induced liver injury (DILI) is a common complication of tuberculosis treatment. We utilised data from the REMoxTB clinical trial to describe the incidence of predisposing factors and the natural history i...

    Authors: Conor Duncan Tweed, Genevieve Helen Wills, Angela M. Crook, Rodney Dawson, Andreas H. Diacon, Cheryl E. Louw, Timothy D. McHugh, Carl Mendel, Sarah Meredith, Lerato Mohapi, Michael E. Murphy, Stephen Murray, Sara Murthy, Andrew J. Nunn, Patrick P. J. Phillips, Kasha Singh…

    Citation: BMC Medicine 2018 16:46

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  10. Content type: Research article

    The U.S. Food and Drug Administration (FDA) often approves new drugs based on trials that use surrogate markers for endpoints, which involve certain trade-offs and may risk making erroneous inferences about th...

    Authors: Joshua D. Wallach, Oriana Ciani, Alison M. Pease, Gregg S. Gonsalves, Harlan M. Krumholz, Rod S. Taylor and Joseph S. Ross

    Citation: BMC Medicine 2018 16:45

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  11. Content type: Research article

    Insufficient sleep duration and obstructive sleep apnea, two common causes of sleep deficiency in adults, can result in excessive sleepiness, a well-recognized cause of motor vehicle crashes, although their co...

    Authors: Daniel J. Gottlieb, Jeffrey M. Ellenbogen, Matt T. Bianchi and Charles A. Czeisler

    Citation: BMC Medicine 2018 16:44

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  12. Content type: Research article

    Refugees may have an increased vulnerability to infectious diseases, and the consequences of an outbreak are more severe in a refugee camp. When an outbreak is suspected, access to clinical information is crit...

    Authors: Amanda M. Rojek, Kassiani Gkolfinopoulou, Apostolos Veizis, Angeliki Lambrou, Lyndsey Castle, Theano Georgakopoulou, Karl Blanchet, Takis Panagiotopoulos and Peter W. Horby

    Citation: BMC Medicine 2018 16:43

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  13. Content type: Research article

    An inverse relationship between allergies with glioma risk has been reported in several but not all epidemiological observational studies. We performed an analysis of genetic variants associated with atopy to ...

    Authors: Linden Disney-Hogg, Alex J. Cornish, Amit Sud, Philip J. Law, Ben Kinnersley, Daniel I. Jacobs, Quinn T. Ostrom, Karim Labreche, Jeanette E. Eckel-Passow, Georgina N. Armstrong, Elizabeth B. Claus, Dora Il’yasova, Joellen Schildkraut, Jill S. Barnholtz-Sloan, Sara H. Olson, Jonine L. Bernstein…

    Citation: BMC Medicine 2018 16:42

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  14. Content type: Research article

    Clusterin, also known as apolipoprotein J (apoJ), is one of the most abundantly expressed apolipoproteins in the brain after apolipoprotein E (apoE). Like the ε4 allele of the apolipoprotein E gene (APOE), the cl...

    Authors: Liv Tybjærg Nordestgaard, Anne Tybjærg-Hansen, Katrine Laura Rasmussen, Børge G. Nordestgaard and Ruth Frikke-Schmidt

    Citation: BMC Medicine 2018 16:39

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  15. Content type: Research article

    Since 2015, Europe has been facing an unprecedented arrival of refugees and migrants: more than one million people entered via land and sea routes. During their travels, refugees and migrants often face harsh ...

    Authors: Jihane Ben Farhat, Karl Blanchet, Pia Juul Bjertrup, Apostolos Veizis, Clément Perrin, Rebecca M. Coulborn, Philippe Mayaud and Sandra Cohuet

    Citation: BMC Medicine 2018 16:40

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  16. Content type: Research article

    Marine resources including fatty fish are important sources of n-3 long chain polyunsaturated fatty acids (n-3 LC-PUFAs), which are important for brain development. To our knowledge, this is the first randomiz...

    Authors: Jannike Øyen, Ingrid Kvestad, Lisa Kolden Midtbø, Ingvild Eide Graff, Mari Hysing, Kjell Morten Stormark, Maria Wik Markhus, Valborg Baste, Livar Frøyland, Berthold Koletzko, Hans Demmelmair, Lisbeth Dahl, Øyvind Lie and Marian Kjellevold

    Citation: BMC Medicine 2018 16:41

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  17. Content type: Research article

    Hyperlactataemia (HL) is a biomarker of disease severity that predicts mortality in patients with sepsis and malaria. Lactate clearance (LC) during resuscitation has been shown to be a prognostic factor of sur...

    Authors: A. Aramburo, Jim Todd, Elizabeth C. George, Sarah Kiguli, Peter Olupot-Olupot, Robert O. Opoka, Charles Engoru, Samuel O. Akech, Richard Nyeko, George Mtove, Diana M. Gibb, Abdel G. Babiker and Kathryn Maitland

    Citation: BMC Medicine 2018 16:37

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  18. Content type: Research article

    Antidepressants are one of the most commonly prescribed medications in young and middle-aged adults, but there is relatively little information on their safety across a range of adverse outcomes in this age gr...

    Authors: Carol Coupland, Trevor Hill, Richard Morriss, Michael Moore, Antony Arthur and Julia Hippisley-Cox

    Citation: BMC Medicine 2018 16:36

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  19. Content type: Research article

    Acute symptomatic seizures and febrile seizures are common in children admitted to hospitals in Africa and may be markers of brain dysfunction. They may be associated with behavioural and emotional problems, b...

    Authors: Symon M. Kariuki, Amina Abubakar, Martha Kombe, Michael Kazungu, Rachael Odhiambo, Alan Stein and Charles R. J. C. Newton

    Citation: BMC Medicine 2018 16:35

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  20. Content type: Correction

    The original article [1] contains a major error whereby all rates in Table 2 are mistakenly presented as 50% of their true values; this error was caused by a miscalculation in annualising the original values t...

    Authors: Matthew J. Spittal, David M. Studdert, Ron Paterson and Marie M. Bismark

    Citation: BMC Medicine 2018 16:38

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    The original article was published in BMC Medicine 2016 14:198

  21. Content type: Research article

    External validations and comparisons of prognostic models or scores are a prerequisite for their use in routine clinical care but are lacking in most medical fields including chronic obstructive pulmonary dise...

    Authors: Beniamino Guerra, Sarah R. Haile, Bernd Lamprecht, Ana S. Ramírez, Pablo Martinez-Camblor, Bernhard Kaiser, Inmaculada Alfageme, Pere Almagro, Ciro Casanova, Cristóbal Esteban-González, Juan J. Soler-Cataluña, Juan P. de-Torres, Marc Miravitlles, Bartolome R. Celli, Jose M. Marin, Gerben ter Riet…

    Citation: BMC Medicine 2018 16:33

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  22. Content type: Debate

    There is increasing focus on the strength of primary health care systems in low and middle-income countries (LMIC). There are important roles for higher quality district hospital care within these systems. The...

    Authors: Mike English, Paul Mwaniki, Thomas Julius, Mercy Chepkirui, David Gathara, Paul O. Ouma, Peter Cherutich, Emelda A. Okiro and Robert W. Snow

    Citation: BMC Medicine 2018 16:32

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