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  1. Content type: Research article

    Most evidence about what works in transitional care comes from small studies in single clinical specialties. We tested the hypothesis that exposures to nine recommended features of transitional healthcare were...

    Authors: A. Colver, H. McConachie, A. Le Couteur, G. Dovey-Pearce, K. D. Mann, J. E. McDonagh, M. S. Pearce, L. Vale, H. Merrick and J. R. Parr

    Citation: BMC Medicine 2018 16:111

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  2. Content type: Research article

    Depression is a prevalent and disabling mental disorder that frequently co-occurs with a wide range of chronic conditions. Evidence has suggested that depression could be associated with excess all-cause morta...

    Authors: Myrela O. Machado, Nicola Veronese, Marcos Sanches, Brendon Stubbs, Ai Koyanagi, Trevor Thompson, Ioanna Tzoulaki, Marco Solmi, Davy Vancampfort, Felipe B. Schuch, Michael Maes, Giovanni A. Fava, John P. A. Ioannidis and André F. Carvalho

    Citation: BMC Medicine 2018 16:112

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  3. Content type: Research article

    As complete reporting is essential to judge the validity and applicability of multivariable prediction models, a guideline for the Transparent Reporting of a multivariable prediction model for Individual Progn...

    Authors: Pauline Heus, Johanna A. A. G. Damen, Romin Pajouheshnia, Rob J. P. M. Scholten, Johannes B. Reitsma, Gary S. Collins, Douglas G. Altman, Karel G. M. Moons and Lotty Hooft

    Citation: BMC Medicine 2018 16:120

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  4. Content type: Research article

    Human papillomavirus (HPV) vaccination is safe and effective in preventing cervical cancer in females. As HPV infections can also induce cancers of the anus, penis and oral cavity, male vaccination is also adv...

    Authors: Thomas Harder, Ole Wichmann, Stefanie J. Klug, Marianne A. B. van der Sande and Miriam Wiese-Posselt

    Citation: BMC Medicine 2018 16:110

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  5. Content type: Research article

    The present study aims to evaluate the cost-effectiveness of the newly introduced varicella and herpes zoster (HZ) vaccination programmes in Italy. The appropriateness of the introduction of the varicella vacc...

    Authors: Alessia Melegaro, Valentina Marziano, Emanuele Del Fava, Piero Poletti, Marcello Tirani, Caterina Rizzo and Stefano Merler

    Citation: BMC Medicine 2018 16:117

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  6. Content type: Research article

    Intensification of metformin monotherapy with additional glucose-lowering drugs is often required in patients with type 2 diabetes (T2D). This study evaluated changes in HbA1c and weight, as well as treatment ...

    Authors: John Wilding, Thomas Godec, Kamlesh Khunti, Stuart Pocock, Robin Fox, Liam Smeeth, Per Clauson, Peter Fenici, Niklas Hammar and Jesús Medina

    Citation: BMC Medicine 2018 16:116

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  7. Content type: Research article

    The RTS,S/AS01 vaccine for Plasmodium falciparum malaria demonstrated moderate efficacy in 5–17-month-old children in phase 3 trials, and from 2018, the vaccine will be evaluated through a large-scale pilot imple...

    Authors: Alexandra B. Hogan, Peter Winskill, Robert Verity, Jamie T. Griffin and Azra C. Ghani

    Citation: BMC Medicine 2018 16:109

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  8. Content type: Research article

    Caregivers may promote the uptake of science into patient care and the practice of evidence-informed medicine. The purpose of this study was to determine whether caregiver-mediated (non-clinical caregiver-deli...

    Authors: Kirsten M. Fiest, Christiane Job McIntosh, Danielle Demiantschuk, Jeanna Parsons Leigh and Henry T. Stelfox

    Citation: BMC Medicine 2018 16:105

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  9. Content type: Research article

    For patients starting treatment for depression, current guidelines recommend titrating the antidepressant dosage to the maximum of the licenced range if tolerated. When patients do not achieve remission within...

    Authors: Tadashi Kato, Toshi A. Furukawa, Akio Mantani, Ken’ichi Kurata, Hajime Kubouchi, Susumu Hirota, Hirotoshi Sato, Kazuyuki Sugishita, Bun Chino, Kahori Itoh, Yoshio Ikeda, Yoshihiro Shinagawa, Masaki Kondo, Yasumasa Okamoto, Hirokazu Fujita, Motomu Suga…

    Citation: BMC Medicine 2018 16:103

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  10. Content type: Research article

    Genotype-guided warfarin dosing has been shown in some randomized trials to improve anticoagulation outcomes in individuals of European ancestry, yet its utility in Asian patients remains unresolved.

    Authors: Nicholas L. Syn, Andrea Li-Ann Wong, Soo-Chin Lee, Hock-Luen Teoh, James Wei Luen Yip, Raymond CS Seet, Wee Tiong Yeo, William Kristanto, Ping-Chong Bee, LM Poon, Patrick Marban, Tuck Seng Wu, Michael D. Winther, Liam R. Brunham, Richie Soong, Bee-Choo Tai…

    Citation: BMC Medicine 2018 16:104

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  11. Content type: Research article

    The effects of community health worker (CHW) home visiting during the antenatal and postnatal periods in fragile- and conflicted-affected countries such as Afghanistan are not known.

    Authors: Karen M. Edmond, Khaksar Yousufi, Zelaikha Anwari, Sayed Masoud Sadat, Shah Mansoor Staniczai, Ariel Higgins-Steele, Alexandra L. Bellows and Emily R. Smith

    Citation: BMC Medicine 2018 16:106

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  12. Content type: Research article

    The Choosing Wisely campaign highlights the importance of clinical reasoning abilities for competent and reflective physicians. The principles of this campaign should be addressed in undergraduate medical educati...

    Authors: Sascha Ludwig, Nikolai Schuelper, Jamie Brown, Sven Anders and Tobias Raupach

    Citation: BMC Medicine 2018 16:107

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  13. Content type: Research article

    Stratification of cancer patients to identify those with worse prognosis is increasingly important. Through in silico analyses, we recently developed a gene expression-based prognostic score (S3-score) for cle...

    Authors: Florian Büttner, Stefan Winter, Steffen Rausch, Jörg Hennenlotter, Stephan Kruck, Arnulf Stenzl, Marcus Scharpf, Falko Fend, Abbas Agaimy, Arndt Hartmann, Jens Bedke, Matthias Schwab and Elke Schaeffeler

    Citation: BMC Medicine 2018 16:108

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  14. Content type: Research article

    Equitable access to vaccines has been suggested as a priority for low- and middle-income countries (LMICs). However, it is unclear whether providing equitable access is enough to ensure health equity. Furtherm...

    Authors: Angela Y. Chang, Carlos Riumallo-Herl, Joshua A. Salomon, Stephen C. Resch, Logan Brenzel and Stéphane Verguet

    Citation: BMC Medicine 2018 16:102

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  15. Content type: Research article

    Autism spectrum disorder (ASD) is a neurodevelopmental disorder with a worldwide prevalence of 1–2%. In low-resource environments, in particular, early identification and diagnosis is a significant challenge. ...

    Authors: T. Heunis, C. Aldrich, J. M. Peters, S. S. Jeste, M. Sahin, C. Scheffer and P. J. de Vries

    Citation: BMC Medicine 2018 16:101

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  16. Content type: Research article

    The Mediterranean Diet (MedDiet) has been acknowledged as a healthy diet. However, its relation with risk of major chronic diseases in non-Mediterranean countries is inconclusive. The Nordic diet is proposed a...

    Authors: Cecilia Galbete, Janine Kröger, Franziska Jannasch, Khalid Iqbal, Lukas Schwingshackl, Carolina Schwedhelm, Cornelia Weikert, Heiner Boeing and Matthias B. Schulze

    Citation: BMC Medicine 2018 16:99

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  17. Content type: Correspondence

    Malaria at international borders presents particular challenges with regards to elimination. International borders share common malaria ecologies, yet neighboring countries are often at different stages of the...

    Authors: Mohammed H. Al Zahrani, Abdiasiis I. Omar, Abdelmohsin M. O. Abdoon, Ali Adam Ibrahim, Abdullah Alhogail, Mohamed Elmubarak, Yousif Eldirdiry Elamin, Mohammed A. AlHelal, Ali M. Alshahrani, Tarig M. Abdelgader, Ibrahim Saeed, Tageddin B. El Gamri, Mohammed S. Alattas, Abdu A. Dahlan, Abdullah M. Assiri, Joseph Maina…

    Citation: BMC Medicine 2018 16:98

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  18. Content type: Research article

    Globally, illness and life expectancy follow a social gradient that puts people of lower socioeconomic status (SES) at higher risk of dying prematurely. Alcohol consumption has been shown to be a factor contri...

    Authors: Charlotte Probst, Charles D. H. Parry, Hans-Ulrich Wittchen and Jürgen Rehm

    Citation: BMC Medicine 2018 16:97

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  19. Content type: Opinion

    The healthcare system has proved a challenging environment for innovation, especially in the area of health services management and research. This is often attributed to the complexity of the healthcare sector...

    Authors: Katrina M. Long, Fiona McDermott and Graham N. Meadows

    Citation: BMC Medicine 2018 16:94

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  20. Content type: Research article

    Despite limited information on neonatal safety, the transfer of frozen-thawed cleavage-stage embryos with blastomere loss is common in women undergoing in vitro fertilization. We aimed to evaluate the pregnanc...

    Authors: Yan-Ting Wu, Cheng Li, Yi-Min Zhu, Shu-Hua Zou, Qiong-Fang Wu, Li-Ping Wang, Yan Wu, Rong Yin, Chao-Yi Shi, Jing Lin, Zi-Ru Jiang, Yi-Jing Xu, Yun-Fei Su, Jian Zhang, Jian-Zhong Sheng, William D. Fraser…

    Citation: BMC Medicine 2018 16:96

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  21. Content type: Research article

    Existing evidence remains inconclusive as to the association between chronic hepatitis B virus (HBV) infection and the risk of chronic kidney disease (CKD). We prospectively examined the association between ch...

    Authors: Jiahui Si, Canqing Yu, Yu Guo, Zheng Bian, Chenxi Qin, Ling Yang, Yiping Chen, Li Yin, Hui Li, Jian Lan, Junshi Chen, Zhengming Chen, Jun Lv and Liming Li

    Citation: BMC Medicine 2018 16:93

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