Advertisement
Review
The driving force behind the current global type 2 diabetes epidemic is insulin resistance in overweight and obese individuals. Dietary factors, physical inactivity, and sedentary behaviors are the major modif...
BMC Medicine 2017 15:171
Published on: 22 September 2017
Research article
Pancreatic carcinoma is one of the most lethal human cancers. In patients with resectable tumors, surgery followed by adjuvant chemotherapy is the only curative treatment. However, the 5-year survival is 20%. ...
BMC Medicine 2017 15:170
Published on: 20 September 2017
Research article
A subanalysis of a randomized clinical trial indicated sepsis survival benefit from interleukin (IL)-1 blockade in patients with features of the macrophage activation-like syndrome (MALS). This study aimed to ...
BMC Medicine 2017 15:172
Published on: 18 September 2017
Research article
Environmental factors, including infectious agents, are speculated to play a role in the rising prevalence and the geographic distribution of celiac disease, an autoimmune disorder. In the USA and Sweden where...
BMC Medicine 2017 15:169
Published on: 15 September 2017
Research article
A highly efficacious vaccine is needed for malaria control and eradication. Immunization with Plasmodium falciparum NF54 parasites under chemoprophylaxis (chemoprophylaxis and sporozoite (CPS)-immunization) induc...
BMC Medicine 2017 15:168
Published on: 13 September 2017
Correspondence
Scientific editors are responsible for deciding which articles to publish in their journals. However, we have not found documentation of their required knowledge, skills, and characteristics, or the existence ...
BMC Medicine 2017 15:167
Published on: 11 September 2017
Research article
As part of the national seasonal influenza vaccination programme in England and Wales, children receive a quadrivalent vaccine offering protection against two influenza A strains and two influenza B strains. H...
BMC Medicine 2017 15:166
Published on: 8 September 2017
Research article
Radiotherapy for head and neck squamous cell carcinomas (HNSCC) is associated with a substantial morbidity and inconsistent efficacy. Human papillomavirus (HPV)-positive status is recognized as a marker of inc...
BMC Medicine 2017 15:165
Published on: 1 September 2017
Research article
While being small-for-gestational-age due to placental insufficiency is a major risk factor for stillbirth, 50% of stillbirths occur in appropriate-for-gestational-age (AGA, > 10th centile) fetuses. AGA fetuse...
BMC Medicine 2017 15:164
Published on: 31 August 2017
Research article
There is an increasing incidence of type 2 diabetes mellitus (T2DM) in young urban South-Asians. We tested the effect of a pragmatic trimonthly lifestyle modification (LSM) programme (P-LSM) versus a less-inte...
BMC Medicine 2017 15:146
Published on: 30 August 2017
Opinion
Personalised treatment that is uniquely tailored to an individual’s phenotype has become a key goal of clinical and pharmaceutical development across many, particularly chronic, diseases. For type 2 diabetes, ...
BMC Medicine 2017 15:163
Published on: 28 August 2017
Research article
In lung cancer screening, a nodule management protocol describes nodule assessment and thresholds for nodule size and growth rate to identify patients who require immediate diagnostic evaluation or additional ...
BMC Medicine 2017 15:162
Published on: 25 August 2017
Research article
Multimorbidity is a major challenge to health systems globally and disproportionately affects socioeconomically disadvantaged populations. We examined socioeconomic inequalities in developing multimorbidity ac...
BMC Medicine 2017 15:152
Published on: 24 August 2017
Research article
Hypertension carries a large societal burden. Obesity is known as a risk factor for hypertension. However, little is known as to whether weight loss interventions reduce the risk of hypertension-related advers...
BMC Medicine 2017 15:161
Published on: 23 August 2017
Commentary
Herein, we summarise the results of the most relevant studies presented at the 2017 ASCO Annual Meeting in the field of soft tissue sarcomas (STSs) and gastrointestinal stromal tumours (GISTs). Innovations on ...
BMC Medicine 2017 15:160
Published on: 22 August 2017
Research article
Conflicting results regarding the impact of repeated vaccination on influenza vaccine effectiveness (VE) may cause confusion regarding the benefits of receiving the current season’s vaccine.
BMC Medicine 2017 15:159
Published on: 21 August 2017
Minireview
Acute gout arthritis flares contribute dominantly to gout-specific impaired health-related quality of life, representing a progressively increasing public health problem. Flares can be complex and expensive to...
BMC Medicine 2017 15:158
Published on: 18 August 2017
Commentary
Advances in deep sequencing technology have led to developments in personalized medicine. Here, we describe the implications of a recent investigation that sequenced ctDNA from the plasma of non-small cell lun...
BMC Medicine 2017 15:157
Published on: 17 August 2017
Commentary
According to data presented at the 2017 American Society of Oncology (ASCO) Annual Meeting, with more than 4 years of follow-up, ibrutinib continues to provide clinical utility in chronic lymphocytic leukemia ...
BMC Medicine 2017 15:156
Published on: 16 August 2017
Research article
Unintended repeat conceptions can result in emotional, psychological and educational harm to young women, often with enduring implications for their life chances. This study aimed to identify which young women...
BMC Medicine 2017 15:155
Published on: 15 August 2017
Research article
Changes in the microvasculature associated with pre-eclampsia and gestational hypertension have been proposed as a potential pathway in the development of cardiovascular disease. We examined whether gestationa...
BMC Medicine 2017 15:153
Published on: 14 August 2017
Research article
The risk of psoriasis in patients with breast cancer is largely unknown, as available evidence is limited to case findings. We systematically examined the incidence and risk factors of psoriasis in patients wi...
BMC Medicine 2017 15:154
Published on: 11 August 2017
Research article
Decreasing trends in measles mortality have been reported in recent years. However, such estimates of measles mortality have depended heavily on assumed regional measles case fatality risks (CFRs) and made lit...
BMC Medicine 2017 15:151
Published on: 10 August 2017
Research article
Recently, health screening recommendations have gone beyond screening for early-stage, asymptomatic disease to include “screening” for presently experienced health problems and symptoms using self-report quest...
BMC Medicine 2017 15:150
Published on: 9 August 2017
Research article
Pregnancy and pregnancy loss may be linked to cardiovascular disease (CVD). However, the evidence is still inconsistent, especially in East Asians, whose reproductive patterns differ importantly from those in ...
BMC Medicine 2017 15:148
Published on: 8 August 2017
