Table 1 Estimates of LE reported in the cART era

Nakagawa et al. [8]

Computer simulation (HIV Synthesis)

UK

LE at birth: 75.0 years if diagnosed with HIV with high CD4 count; 71.5 years if diagnosed with HIV with low CD4 count

LE at birth: estimated from model to be 82.0 years if not infected with HIV

The Antiretroviral Therapy Cohort Collaboration [9]

ART-CC

Multi-country study (Europe and North America)

LE at age 20: 43.1 years. LE at age 35: 31.7 years

Not stated

Johnson et al. [10]

IeDEA-SA

South Africa

LE at age 20: 27.6 years in men; 36.8 years in women. LE at age 60: 10.1 years in men; 14.4 years in women

Not stated

Mills et al. [11]

The AIDS Support Organization (TASO) cohort

Uganda

LE at age 20: 26.7 years. LE at age 35 years: 27.9 years

LE at age 20: 41 years

Losina et al.[12]

Computer simulation (CEPAC)

USA

LE at age 33: 22.66 years if optimally diagnosed and treated; 19.36 years if treated with cART and adherence follows normal patterns

LE at age 33: 42.91 years for general population; 34.58 years if risk profile similar to those with HIV

Bor et al. [17]

KwaZulu-Natal, South Africa

No specific estimates

LE at birth: 52.3 years in 2000; 49.2 years in 2003; 60.5 years in 2011

Lohse et al. [21]

Danish HIV Cohort Study

Denmark

LE at age 25: 8 years in 1995 to 1996; 23 years in 1997 to 1999; 33 years in 2000 to 2005

LE at age 25: 51 years

May et al. [23]

UK Collaborative HIV Cohort Study

UK

LE at age 20: 39.5 years in men; 50.2 years in women. LE at age 35: 30.1 years in men; 37.7 years in women

LE at age 20: 57.8 years in men; 61.6 years in women. LE at age 35: 43.5 years in men; 46.9 years in women

van Sighem et al. [41]

ATHENA Cohort

The Netherlands

LE at age 25: 52.7 years in men; 57.8 years in women

LE at age 25: 53.1 years in men; 58.1 years in women