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Table 4 Change in immunostaining of carcinoma cells between pre-treatment and post-treatment, assessed by semi-quantitative analysis (n = 92)

From: Selective intra-arterial infusion of rAd-p53 with chemotherapy for advanced oral cancer: a randomized clinical trial

 

Groupa

P-value

I (n = 33)

II (n = 30)

III (n = 29)

Bax immunostaining, n (%)

    

 Decrease

0 (0.0)

0 (0.0)

1 (3.4)

<0.001b

 No change

5 (15.2)

3 (10.0)

27 (93.1)

 Increase

28 (84.8)

27 (90.0)

1 (3.4)

Bcl-2 immunostaining, n (%)

    

 Decrease

30 (90.9)

24 (80.0)

8 (27.6)

<0.001b

 No change

3 (9.1)

4 (13.3)

18 (62.1)

 Increase

0 (0.0)

2 (6.7)

3 (10.3)

  1. aGroup I: chemotherapy and rAD-p53; group II: rAD-p53; group III: chemotherapy.
  2. b P-values are based on Fisher’s exact test.