From: Risk of ischemic stroke in patients with ovarian cancer: a nationwide population-based study
Predictive variables | Univariate analysis | Multivariate analysisa | ||
---|---|---|---|---|
 | HR (95% CI) | P | HR (95% CI) | P |
Age ≥50 | 3.25 (2.49 to 4.25) | <0.001 | 2.21(1.64 to 2.99) | <0.001 |
Comorbidities | Â | Â | Â | Â |
  Diabetes mellitus | 2.84 (2.19 to 3.67) | <0.001 | 1.71(1.27 to 2.29) | <0.001 |
  Hypertension | 3.15 (2.47 to 4.00) | <0.001 | 1.84(1.39 to 2.43) | <0.001 |
  Chronic kidney disease | 1.64 (1.12 to 2.39) | 0.011 | 1.05(0.71 to 1.56) | 0.791 |
  Dyslipidemia | 2.25 (1.75 to 2.89) | <0.001 | 1.09(0.81 to 1.46) | 0.569 |
  Coronary artery disease | 3.66 (1.36 to 9.83) | 0.010 | 2.01(0.74 to 5.42) | 0.169 |
  Atrial fibrillation | 0.75 (0.11 to 5.31) | 0.769 |  |  |
  Peripheral arterial occlusive disease | 3.09 (0.43 to 22.02) | 0.261 |  |  |
Treatment b | Â | Â | Â | Â |
  Surgeryc | 0.83 (0.64 to 1.06) | 0.138 |  |  |
  Chemotherapy | 1.67 (1.25 to 2.25) | 0.001 | 1.45(1.07 to 1.97) | 0.017 |
  Cisplatin-based | 1.35 (1.06 to 1.73) | 0.017 | 1.38(1.07 to 1.76) | 0.012 |
  Carboplatin-based | 1.76 (1.37 to 2.25) | <0.001 | 1.46(1.13 to 1.89) | 0.004 |
  Non-platinum-based | 1.24 (0.68 to 2.26) | 0.490 | 1.12(0.61 to 2.04) | 0.722 |