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Table 3 Mean onset ages stratified by LRRK2 mutations and sex are shown

From: The Gly2019Ser mutation in LRRK2is not fully penetrant in familial Parkinson's disease: the GenePD study

 

G2019S

R1441C

No LRRK2 mutations

 

Men

Women

Men

Women

Men

Women

No. of cases (%)

32 (53.3%)

28 (46.7%)

1 (25%)

3 (75%)

549 (56.9%)

416 (43.1%)

Mean onset age

60.0

59.9

53.0

67.0

60.0

59.7

No. of familial cases (%)

29 (53.7%)

25 (46.3%)

1 (25%)

3 (75%)

471 (55.7%)

374 (44.3%)

Mean onset age

59.9

59.3

53.0

67.0

60.9

59.9

No. of idiopathic cases (%)

3 (50%)

3 (50%)

0

0

78 (65.0%)

42 (35.0%)

Mean onset age

61.0

64.3

-

-

55.0

57.7

  1. No significant differences in onset age were detected in any category.