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Table 1 Baseline characteristics of patients stratified according to outcome (n = 1,521)

From: The predictive value of current haemoglobin levels for incident tuberculosis and/or mortality during long-term antiretroviral therapy in South Africa: a cohort study

 

All (n = 1,521)

Alive (n = 810)

Died (n = 192)

LTFU (n = 314)

Transfer-out (n = 205)

P -value ¥

Age (at baseline), median (IQR)

33 (28-33)

33 (29-38)

35 (29-43)

31 (27-36)

32 (28-38)

<0.001#

Gender

      

Male

451 (29.7)

235 (29.0)

77 (40.1)

92 (29.3)

47 (22.9)

0.002

Female

1,070 (70.4)

575 (71.0)

115 (59.9)

222 (70.7)

158 (77.1)

 

WHO disease stage (at baseline)

      

1 or 2

302 (19.9)

184 (22.7)

14 (7.3)

64 (20.4)

40 (19.5)

<0.001

3 or 4

1219 (80.1)

626 (77.3)

178 (92.7)

250 (79.6)

165 (80.5)

 

CD4 cell count (cells/μL), median, IQR a

101 (49-158)

102 (53-160)

77 (25-138)

108 (53-168)

107 (48-151)

<0.001

CD4 category

      

≥200

173 (11.6)

98 (12.4)

15 (7.9)

39 (12.8)

21 (10.5)

0.072

100-199

582 (39.1)

311(39.2)

61 (32.1)

126 (41.2)

84 (41.8)

 

<100

735 (49.3)

384 (48.4)

114 (60.0)

141 (46.1)

96 (47.8)

 

HIV viral load (log copies/mL), median (IQR) b

4.8 (4.4-5.3)

4.8 (4.4-5.2)

5.0 (4.6-5.4)

4.8 (4.3-5.2)

4.8 (4.3-5.2)

0.003

Haemoglobin (g/dL) c

      

Median, IQR

11.2 (9.8-12.5)

11.3 (10.0-12.6)

10.5 (9.3-12.3)

11.3 (10.0-12.3)

10.9 (9.7-12.2)

0.028

WHO anaemia severity c

      

None

318 (27.9)

185 (30.4)

33 (21.9)

66 (29.0)

34 (22.4)

0.048

Mild

304 (26.7)

163 (26.8)

34 (22.5)

67 (29.4)

40 (26.3)

 

Moderate

469 (41.1)

235 (38.6)

74 (49.0)

85 (37.3)

75 (49.3)

 

Severe

49 (4.3)

26 (4.3)

10 (6.6)

10 (4.4)

3 (2.0)

 

TB disease status

      

Past history of TB

710 (46.7)

368 (45.5)

116 (60.4)

133 (42.4)

93 (45.4)

0.001

Prevalent TB

452 (29.7)

211 (26.1)

72 (37.5)

103 (32.8)

66 (32.2)

0.005#

Any incident TB

423 (27.8)

232 (28.6)

59 (30.7)

83 (26.5)

49 (23.9)

0.405

Any TB ever (including past history, prevalent and incident TB)

1,147(75.4)

599 (74.0)

165 (85.9)

229 (72.9)

154 (75.1)

0.004

  1. Abbreviations:IQR interquartile range, TB tuberculosis, WHO World Health Organization.
  2. a31 missing values, b101 missing values, c 381 missing values.
  3. All values are numbers (%) unless otherwise stated.
  4. ¥P-value tests for a difference across all groups; #P-value < 0.05 for a difference between those who were LTFU during ART and those who remained alive and in programme. There was no evidence to suggest a difference (P < 0.05) between any baseline characteristics of those who transferred out of the ART programme and those who remained alive and in programme.
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BMC Medicine

ISSN: 1741-7015

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