Table 2 Hazard ratios (HR) and 95% confidence intervals (95% CIs) for CRC-related and overall mortality among CRC survivors according to categories of the WCRF/AICR score

Score range (men)/(women)

(0–2)/(0–3)

(2.25–2.75)/ (3.25–3.75)

(3–3.75)/(4–4.75)

(4–6)/(5–7)

All

CRC-related mortality

No. of deaths (%)

206 (29.1)

260 (27.0)

283 (25.3)

123 (24.5)

Age- and country-adjusted^a

HR (95% CI)

1.00 (reference)

0.92 (0.76–1.11)

0.77 (0.64–0.93)

0.72 (0.57–0.91)

0.001

Multivariate adjusted^b

HR (95% CI)

1.00 (reference)

0.87 (0.72–1.06)

0.74 (0.61–0.90)

0.70 (0.56–0.89)

<0.0001

Overall mortality

No. of deaths (%)

255 (36.1)

330 (34.2)

359 (32.1)

169 (33.6)

Age- and country-adjusted^a

HR (95% CI)

1.00 (reference)

0.94 (0.79–1.10)

0.79 (0.67–0.93)

0.79 (0.65–0.97)

0.002

Multivariate adjusted^b

HR (95% CI)

1.00 (reference)

0.89 (0.75–1.06)

0.77 (0.66–0.92)

0.79 (0.65–0.98)

0.004

Men

CRC-related mortality

No. of deaths (%)

94 (31.0)

122 (28.1)

130 (24.5)

62 (27.0)

Age- and country-adjusted^a

HR (95% CI)

1.00 (reference)

1.01 (0.77–1.34)

0.80 (0.60–1.05)

0.79 (0.56–1.12)

0.050

Multivariate adjusted^b

HR (95% CI)

1.00 (reference)

0.92 (0.69–1.22)

0.74 (0.54–0.96)

0.69 (0.48–0.99)

0.009

Overall mortality

No. of deaths (%)

118 (38.9)

162 (37.3)

164 (30.9)

87 (37.8)

Age- and country-adjusted^a

HR (95% CI)

1.00 (reference)

1.00 (0.79–1.28)

0.76 (0.59–0.97)

0.78 (0.58–1.06)

0.014

Multivariate adjusted^b

HR (95% CI)

1.00 (reference)

0.94 (0.73–1.21)

0.72 (0.56–0.93)

0.71 (0.52–0.97)

0.004

Women

CRC-related mortality

No. of deaths (%)

112 (27.7)

138 (26.0)

153 (26.0)

61 (22.3)

Age- and country-adjusted^a

HR (95% CI)

1.00 (reference)

0.86 (0.66–1.11)

0.77 (0.60–0.99)

0.67 (0.48–0.92)

0.008

Multivariate adjusted^b

HR (95% CI)

1.00 (reference)

0.81 (0.62–1.06)

0.75 (0.57–0.97)

0.72 (0.51–1.00)

0.027

Overall mortality

No. of deaths (%)

137 (33.9)

168 (31.7)

195 (33.2)

82 (30.0)

Age- and country-adjusted^a

HR (95% CI)

1.00 (reference)

0.88 (0.70–1.11)

0.83 (0.67–1.05)

0.78 (0.59–1.03)

0.062

Multivariate adjusted^b

HR (95% CI)

1.00 (reference)

0.86 (0.68–1.09)

0.82 (0.65–1.04)

0.88 (0.66–1.18)

0.242