Days | No granuloma (0) | Small granuloma (+) | Medium granuloma (++) | Large granuloma (+++) | Total |
---|
D45 | 2 % | 13 % | 24 % | 61 % | 100 % |
D135 | 2 % | 14 % | 31 % | 54 % | 100 % |
D180 | 36 % | 22 % | 9 % | 19 % | 100 % |
D270 | 71 % | 19 % | 10 % | 0 % | 100 % |
- Whole TA muscle from three injected animals per time point (n = 3 per time point) were serially cryo-sectionned (a mean number of 90 longitudinal muscle sections were obtained per animal). Each section was categorized into four groups: no granuloma (0), small (+), medium (++) and large (+++) granuloma. Then, percentage of muscle section typing was calculated at each time point