Table 7 Total knee replacement economic results
Difference (intervention – control) a | ||||
|---|---|---|---|---|
N | Mean | (95 % CI) | P value | |
MAIN ANALYSIS: NHS and personal social services (PSS) perspective | ||||
Mean QALY gain | 316 | 0.009 | (−0.030 to 0.049) | 0.64 |
Mean NHS+PSS Cost difference | 316 | –£77 | (£–451 to £296) | 0.68 |
Incremental net monetary benefit – lambda £10,000 | 316 | £171 | (£–452 to £793) | 0.59 |
Incremental net monetary benefit – lambda £20,000 | 316 | £264 | (£–710 to £1,238) | 0.60 |
Incremental net monetary benefit – lambda £30,000 | 316 | £357 | (£–992 to £1,707) | 0.60 |
SECONDARY ANALYSIS: NHS perspective only | ||||
Mean QALY gain | 316 | 0.009 | (−0.030 to 0.049) | 0.64 |
Mean NHS cost difference | 316 | –£74 | (£–414 to £266) | 0.67 |
Incremental net monetary benefit – lambda £20,000 | 316 | 260 | (£–690 to £1,210) | 0.59 |
SENSITIVITY ANALYSIS: using macro-costed prescribed medications | ||||
Prescribed medications b | 316 | –£14 | (£–21 to £ –6) | |
Mean QALY gain | 316 | 0.009 | (−0.030 to 0.049) | 0.64 |
Mean NHS+PSS cost difference | 316 | –£121 | (£–491 to £249) | 0.52 |
Incremental net monetary benefit – lambda £20,000 | 316 | £308 | (£–665 to £1,281) | 0.53 |
SENSITIVITY ANALYSIS: 50 % higher local inpatient costs | ||||
Initial inpatient stay b | 316 | –£258 | (£164 to £353) | |
Mean QALY gain | 316 | 0.008 | (−0.032 to 0.047) | 0.70 |
Mean NHS+PSS cost difference | 316 | –£2 | (£–483 to £478) | 0.99 |
Incremental net monetary benefit – lambda £20,000 | 316 | £159 | (£–882 to £1,200) | 0.76 |
SENSITIVITY ANALYSIS: 50 % lower local inpatient costs | ||||
Initial inpatient stay b | 316 | £84 | (£–66 to £234) | |
Mean QALY gain | 316 | 0.006 | (−0.034 to 0.045) | 0.79 |
Mean NHS+PSS cost difference | 316 | –£143 | (£–423 to £137) | 0.32 |
Incremental net monetary benefit – lambda £20,000 | 316 | £253 | (£–674 to £1,180) | 0.59 |