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Table 3 Results from multivariable Poisson regression models of association between current receipt of ABC and MI rate, overall and stratified by calendar period. Factors included in adjusted analyses are listed in the Methods section

From: Is there continued evidence for an association between abacavir usage and myocardial infarction risk in individuals with HIV? A cohort collaboration

 

MI/PYRS

Rate (95 % CI)/100 PYRS

aRR (95 % CI)

Overall

 Not currently on ABC

600/295,642

0.20 (0.19, 0.22)

1

 Currently on ABC

341/71,917

0.47 (0.42, 0.52)

1.98 (1.72, 2.29)

Pre-March 2008

 Not currently on ABC

425/169,417

0.25 (0.23, 0.28)

1

 Currently on ABC

247/40,833

0.61 (0.53, 0.68)

1.97 (1.68, 2.33)

Post-March 2008

 Not currently on ABC

175/126,225

0.14 (0.12, 0.16)

1

 Currently on ABC

94/31,084

0.30 (0.24, 0.36)

1.97 (1.43, 2.72)

 Interaction P value

  

0.74

  1. ABC abacavir, aRR adjusted rate ratio, CI confidence interval, MI myocardial infarction, PYRS person-years