Association of circulating neuregulin 4 with metabolic syndrome in obese adults: a cross-sectional study

Table 4 Odds ratios of components of metabolic syndrome according to serum neuregulin 4 (Nrg4)

Components of metabolic syndrome	OR	95 % CI	P value
Model 1
Raised blood pressure	0.814	0.658–1.006	0.057
Raised fasting glucose	0.809	0.657–0.997	0.047
Raised triglycerides	0.987	0.806–1.208	0.899
Reduced HDL-cholesterol	0.999	0.803–1.243	0.991
Metabolic syndrome	0.769	0.621–0.952	0.016
Model 2
Raised blood pressure	0.824	0.662–1.026	0.084
Raised fasting glucose	0.838	0.674–1.042	0.112
Raised triglycerides	1.034	0.838–1.277	0.754
Reduced HDL-cholesterol	1.047	0.836–1.312	0.689
Metabolic syndrome	0.615	0.450–0.841	0.002
Model 3
Raised blood pressure	0.822	0.660–1.024	0.080
Raised fasting glucose	0.806	0.635–1.022	0.075
Raised triglycerides	1.023	0.827–1.266	0.834
Reduced HDL-cholesterol	1.048	0.837–1.314	0.681
Metabolic syndrome	0.603	0.439–0.828	0.002

OR odds ratio, CI confidence interval, BMI body mass index, HOMA-IR homeostasis model assessment of insulin resistance
Model 1: adjusted for age, gender, smoking, alcohol consumption and physical activity
Model 2: adjusted for model 1 + BMI, SBP, glucose, total cholesterol, triglyceride and HDL-c
Model 3: adjusted for model 2 + HOMA-IR and body fat mass

ISSN: 1741-7015