Table 2 General patterns of treatment according to study population
All patients | Patients alive at 5 years | Patients treated with chemotherapy | ||||
|---|---|---|---|---|---|---|
(n = 2165) | (n = 224) | (n = 1575) | ||||
n | % | n | % | |||
Metastatic treatment received | ||||||
Best supportive care only | 340 | 15.70 | 13 | 5.80 | 0 | 0.00 |
Locoregional treatment | 1054 | 48.68 | 187 | 83.48 | 804 | 51.05 |
Surgery | 408 | 38.71 | 82 | 43.85 | 282 | 35.07 |
Radiotherapy | 254 | 24.10 | 12 | 6.42 | 213 | 26.49 |
Radiofrequency | 42 | 3.98 | 9 | 4.81 | 33 | 4.10 |
Other | 30 | 2.85 | 3 | 1.60 | 19 | 2.36 |
Combination | 320 | 30.36 | 81 | 43.32 | 257 | 31.97 |
None | 1111 | 51.32 | 37 | 16.52 | 771 | 48.95 |
Chemotherapy | 1575 | 72.75 | 156 | 69.64 | 1575 | 100 |
None | 590 | 27.25 | 68 | 30.36 | – | – |
1 line | 489 | 22.59 | 54 | 34.62 | 489 | 31.05 |
2 lines | 293 | 13.53 | 24 | 15.38 | 293 | 18.60 |
3 lines | 240 | 11.09 | 21 | 13.46 | 240 | 15.24 |
4 lines | 157 | 7.25 | 11 | 7.05 | 157 | 9.97 |
> 4 lines | 396 | 17.27 | 46 | 29.49 | 396 | 25.15 |
Anthracycline received | ||||||
Yes | – | – | 109 | 69.87 | 951 | 60.38 |
No | – | – | 47 | 30.13 | 624 | 39.62 |
Anthracycline received as first line | ||||||
Yes | – | – | 98 | 62.82 | 852 | 54.10 |
No | – | – | 58 | 37.18 | 723 | 45.90 |
Polychemotherapy received as first line | ||||||
Yes | – | – | 95 | 60.90 | 716 | 45.46 |
No | – | – | 61 | 39.10 | 859 | 54.54 |
Inclusion in a clinical trial | ||||||
Yes: | – | – | 55 | 35.26 | 332 | 21.08 |
Line 1 | – | – | 10 | 6.41 | 122 | 7.75 |
Line 2 | – | – | 17 | 16.67 | 107 | 9.85 |
Line 3 | – | – | 10 | 12.82 | 56 | 7.06 |
Line 4 | – | – | 7 | 12.28 | 30 | 5.42 |
Other lines | – | – | 11 | 23.91 | 17 | 4.29 |
No | – | – | 101 | 64.74 | 1243 | 78.92 |
Off-label drugs | ||||||
Yes: | – | – | 99 | 63.46 | 810 | 51.43 |
Line 1 | – | – | 21 | 13.46 | 194 | 12.32 |
Line 2 | – | – | 22 | 21.57 | 203 | 18.69 |
Line 3 | – | – | 14 | 17.95 | 169 | 21.31 |
Line 4 | – | – | 21 | 36.84 | 142 | 25.68 |
Other lines | – | – | 21 | 45.65 | 102 | 25.76 |
No | – | – | 57 | 36.54 | 765 | 48.57 |