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Table 1 QUADAS-2 results for studies of FIT assays

From: Faecal immunochemical tests (FIT) can help to rule out colorectal cancer in patients presenting in primary care with lower abdominal symptoms: a systematic review conducted to inform new NICE DG30 diagnostic guidance

Study

Risk of bias

Applicability concerns

Patient selection

Index test

Reference standard

Flow and timing

Patient

Index test

Reference standard

Auge 2016 [34]

Low

Low

Low

Low

High

Low

Low

Cubiella 2014 [31]

Low

Low

Low

Low

High

Low

Low

Godber 2016 [33]

Low

Low

Unclear

Low

High

Low

Low

Krivec 2011 [30]

Unclear

High

Unclear

Unclear

High

Low

High

McDonald 2013 [32]

Low

Low

Unclear

High

High

Low

Unclear

Mowat 2015 [28]

Low

Low

Low

High

High

Low

Low

Rodríguez-Alonso 2015 [29]

Unclear

Low

Low

Low

High

Low

Low

Terhaar sive Droste 2011 [35]

Low

Low

Low

Unclear

High

Low

Low

Thomas 2016 [52]

Unclear

Low

Unclear

High

High

Low

Low