Direct meta- analysis MSC meta- analysis | GOLD | B-AE-D | GOLD (2011–2016) | DOSE | BODEx | SAFE | eBODE | BODE | BODE updated | ADO | |
---|---|---|---|---|---|---|---|---|---|---|---|
1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | ||
GOLD | A | AUC = 0.613 (1st Qu. 0.587, 3rd Qu. 0.637) | ΔAUC = 0.030 (−0.005, 0.065) | 0.017 (−0.005, 0.038) | 0.036 (0.008, 0.064) | 0.054 (0.029, 0.079) | 0.047 (0.027, 0.068) | 0.064 (0.004, 0.123) | 0.071 (0.040, 0.102) | 0.080 (0.041, 0.119) | 0.090 (0.072, 0.109) |
B-AE-D | B | ΔAUC = 0.010 (−0.010, 0.031) | −0.004 (−0.025, 0.017) | 0.004 (− 0.012, + 0.020) | 0.025 (0.011, 0.039) | NA | 0.069 (−0.016, −0.121) | 0.079 (0.004, 0.154) | 0.082 (−0.012, −0.152) | 0.076 (0.051, 0.101) | |
GOLD (2011–2016) | C | 0.012 (−0.001, 0.024) | 0.001 (− 0.019, 0.021) | 0.009 (− 0.002, 0.021) | 0.028 (0.017, 0.039) | 0.055 (0.038, 0.072) | 0.047 (0.016, 0.079) | 0.059 (0.046, 0.073) | 0.051 (0.027, 0.076) | 0.067 (0.053, 0.080) | |
DOSE | D | 0.022 (0.006, 0.037) | 0.011 (−0.007, − 0.029) | 0.010 (− 0.005, 0.025) | 0.018 (0.008, −0.029) | NA | 0.039 (0.007, 0.070) | 0.033 (−0.000, 0.065) | 0.043 (−0.002, 0.088) | 0.061 (−0.044, −0.079) | |
BODEx | E | 0.041 (0.027, 0.055) | 0.030 (0.014, 0.047) | 0.029 (0.015, 0.043) | 0.019 (0.005, 0.033) | NA | 0.030 (−0.001, 0.061) | 0.031 (−0.017, 0.079) | 0.039 (−0.028, 0.105) | 0.050 (0.034, 0.066) | |
SAFE | F | 0.061 (0.034, 0.087) | 0.050 (0.018, 0.082) | 0.049 (0.022, 0.076) | 0.039 (0.010, 0.068) | 0.020 (−0.009, 0.048) | NA | 0.011 (−0.000, 0.023) | 0.005 (−0.009, 0.018) | −0.007 (−0.029, 0.015) | |
eBODE | G | 0.065 (0.046, 0.085) | 0.055 (0.032, 0.078) | 0.054 (0.034, 0.074) | 0.044 (0.023, 0.064) | 0.024 (0.007, 0.042) | 0.005 (−0.025, 0.035) | −0.001 (−0.020, 0.017) | 0.002 (−0.031, 0.034) | 0.024 (−0.018, 0.066) | |
BODE | H | 0.068 (0.052, 0.084) | 0.057 (0.034, 0.080) | 0.056 (0.039, 0.074) | 0.046 (−0.027, −0.065) | 0.027 (0.009, 0.045) | 0.007 (−0.019, 0.034) | 0.003 (−0.016, 0.021) | 0.005 (−0.006, 0.017) | −0.004 (−0.023, 0.016) | |
BODE upd. | I | 0.076 (0.058, 0.095) | 0.066 (0.041, 0.091) | 0.065 (0.045, 0.085) | 0.055 (−0.033, −0.076) | 0.036 (0.015, 0.056) | 0.016 (−0.012, 0.043) | 0.011 (−0.009, 0.031) | 0.008 (−0.005, 0.022) | −0.005 (−0.032, 0.022) | |
ADO | L | 0.083 (0.070, 0.096) | 0.072 (0.052, 0.093) | 0.071 (0.056, 0.087) | 0.070 (−0.052, −0.089) | 0.042 (0.026, 0.058) | 0.022 (−0.005, 0.050) | 0.018 (−0.003, 0.038) | 0.015 (−0.002, 0.032) | 0.007 (−0.012, 0.026) |