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Table 2 Long-term effects of exercise on fatigue and physical activity among colon and breast cancer patients

From: Four-year effects of exercise on fatigue and physical activity in patients with cancer

 

Baseline

Baseline to 4 years post-intervention

 

Within-group differences

Between-group differences

Mean

SD

Mean [95% CI]

Mean [95% CI]

Effect size

Multidimensional Fatigue Inventory (MFI)

 General fatigue

I

10.24

4.92

−0.41 [−1.52, 0.71]

−0.38 [−1.63, 0.86]

0.08

UC

10.67

4.80

−0.63 [− 1.81, 0.56]

Reference

 

 Physical fatigue

I

9.92

5.12

−1.00 [−2.17, 0.18]

− 1.13 [−2.45, 0.20]

0.22

UC

10.54

5.01

−0.55 [−1.79, 0.70]

Reference

 

 Mental fatigue

I

9.77

5.33

−0.23 [−1.40, 0.94]

− 0.30 [− 1.64, 1.05]

0.06

UC

9.96

5.20

−0.24 [−1.48, 1.00]

Reference

 

 Reduced activity

I

8.18

4.11

−0.38 [−1.28, 0.53]

− 0.17 [− 1.23, 0.90]

0.04

UC

8.91

4.02

−0.98 [−1.94,  –0.02]*

Reference

 

 Reduced motivation

I

8.36

5.51

0.72 [−0.41, 1.85]

−0.18 [− 1.15, 0.79]

0.03

UC

9.17

5.83

0.40 [−0.81, 1.61]

Reference

 

Short Questionnaire of Assess Health-enhancing physical activity (SQUASH)

 Total physical activity

I

UC

583.91

627.31

658.73

637.11

43.22 [− 102.13, 188.57]

− 143.77 [− 298.43, 10.89]

141.46 [1.31, 281.61]*

Reference

0.22

 Sport and leisure physical activity

I

UC

220.08

227.34

269.27

259.91

85.18 [30.65, 139.72]*

54.67 [−3.75, 113.09]

20.41 [−45.54, 86.36]

Reference

0.08

  1. I exercise intervention group, UC usual care group, SD standard deviation, CI confidence interval
  2. *Statistically significant (p < 0.05)
  3. Between-group effects were assessed using mixed models including the measurements obtained at 18 and 36 weeks and 4 years, adjusted for the value of the outcome variable at baseline as well as for stratification factors: age, radiotherapy, hospital, and tumor site. Within-group effects were assessed using mixed models including the measurements obtained at baseline, 18 and 36 weeks, and 4 years, adjusted for stratification factors: age, radiotherapy, hospital, and tumor site
  4. Baseline results and within-group differences were based on participants having baseline measurements. Between-group differences were based on participants having measurements at 18 weeks, 36 weeks, or 4 years