Fig. 2

Examples of selection for single-dose artemisinin resistance. Demonstrative parasitemia trends as seen at different time points during the resistance-selection process are shown from mice that received single flash doses of (a) 15 mg/kg, (b) 120 mg/kg, or (c) 240 mg/kg artesunate. Arrows indicate day of intravenous drug delivery. Results were reproduced in several mice as indicated in Table 1 and Table S2A