Fig. 4
Geometric mean kinetics of the P. falciparum-specific IgG subclass response. The geometric mean antibody kinetics over time in each of the exposure groups relative to the collection of the first sample at time t = 0. Each panel represents the IgG subclass response of a particular antigen specificity. Blue, red, green, and yellow denote the IgG1, IgG2, IgG3, and IgG4 response, respectively. Solid lines represent the previously exposed and the dashed lines the previously naïve. The antibody levels in arbitrary antibody units are directly comparable only within the antigen and IgG subclass. The dotted line represents the assay lower limit of quantification. The estimated population-level parameters with corresponding variance parameters are available in Additional file 2: Table S1