The XN-30 hematology analyzer for rapid sensitive detection of malaria: a diagnostic accuracy study

Table 4 Prevalence of disease on qPCR, N (%, 95% CI) *McNemar test to compare sensitivity and specificity present. All ratios presented as XN-30 relative to microscopy

	XN-30 and microscopy versus qPCR results (n = 837)
	XN-30		Microscopy		Test ratio (95% CI)	p value
	Positive	Negative	Positive	Negative
qPCR > 0.05 p/μL	253	104	237	120
qPCR < 0.05 p/μL	2	478	0	480
Sensitivity	70.9%		66.4%		0.94 (0.90–0.97)	.0009
Specificity	99.6%		100.0%		0	.5
PPV	98.9%		100.0%
NPV	83.4%		80.0%
ROC	0.86		0.83

qPCR qualitative polymerase chain reaction, PPV positive predictive value, NPV negative predictive value

ISSN: 1741-7015