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Table 3 Performance of serological markers for a diagnosis of celiac disease

From: Celiac disease: a comprehensive current review

 

Sensitivity (%)

Specificity (%)

PPV (%)

NPV (%)

Diagnostic accuracy (%)

Anti-tTG IgA

96.8

91.0

91.2

96.8

97.7

EmA IgA

93.7

100

100

94.4

96.9

DGP IgG

84.4

98.5

98.2

86.8

91.6

  1. Anti-tTG anti-transglutaminase antibodies, DGP direct antibodies against deamidated gliadin peptides, EmA anti-endomysium antibodies, NPV negative predictive value, PPV positive predictive value