Characteristics | No NSAIDs | Aspirin | Non-aspirin NSAIDs | Both NSAIDs |
---|---|---|---|---|
Number | 194,198 | 58,761 | 49,059 | 14,886 |
Year of cancer diagnosis (%) | ||||
2006–2009 | 86,249 (44.4) | 26,731 (45.5) | 23,287 (47.5) | 7411 (49.8) |
2010–2013 | 107,949 (55.6) | 32,030 (54.5) | 25,772 (52.5) | 7475 (50.2) |
Sex (%) | ||||
Male | 99,678 (51.3) | 36,861 (62.7) | 23,780 (48.5) | 8910 (59.9) |
Female | 94,520 (48.7) | 21,900 (37.3) | 25,279 (51.5) | 5976 (40.1) |
Age at cancer diagnosis, mean [SD], years (%) | 65.7 [13.0] | 75.4 [9.5] | 64.8 [11.8] | 73.3 [9.2] |
Educational levela (%) | ||||
Low | 63,369 (32.6) | 27,762 (47.2) | 15,859 (32.3) | 6546 (44.0) |
Medium | 76,981 (39.6) | 20,699 (35.2) | 20,420 (41.6) | 5590 (37.6) |
High | 51,399 (26.5) | 9267 (15.8) | 12,221 (24.9) | 2513 (16.9) |
Unknown | 2449 (1.3) | 1033 (1.8) | 559 (1.1) | 237 (1.6) |
Occupation (%) | ||||
Blue-collar | 28,227 (14.5) | 2772 (4.7) | 8472 (17.3) | 901 (6.1) |
White-collar | 46,049 (23.7) | 4163 (7.1) | 10,959 (22.3) | 1215 (8.2) |
Not working | 119,190 (61.4) | 51,743 (88.1) | 29,460 (60.1) | 12,742 (85.6) |
Unclassified or unknown | 732 (0.4) | 83 (0.1) | 168 (0.3) | 28 (0.2) |
Region of residenceb (%) | ||||
East | 71,206 (36.7) | 19,957 (34.0) | 17,831 (36.3) | 4903 (32.9) |
South | 87,891 (45.3) | 26,708 (45.5) | 22,503 (45.9) | 6834 (45.9) |
North | 35,101 (18.1) | 12,096 (20.6) | 8725 (17.8) | 3149 (21.2) |
Marital status (%) | ||||
Unmarried | 29,383 (15.1) | 4990 (8.5) | 6355 (13.0) | 1101 (7.4) |
Married/registered partnership | 108,123 (55.7) | 31,120 (53.0) | 28,141 (57.4) | 8242 (55.4) |
Divorced/separated | 30,803 (15.9) | 8474 (14.4) | 8734 (17.8) | 2441 (16.4) |
Widow(er)/surviving partner | 25,889 (13.3) | 14,177 (24.1) | 5829 (11.9) | 3102 (20.8) |
Chronic disease scorec (%) | ||||
0 | 80,567 (41.5) | 25 (0.0) | 15,061 (30.7) | 19 (0.1) |
1–3 | 95,079 (49.0) | 25,849 (44.0) | 29,061 (59.2) | 5792 (38.9) |
> 3 | 18,552 (9.6) | 32,887 (56.0) | 4937 (10.1) | 9075 (61.0) |
Diagnosis of potential indications for NSAIDsd (%) | ||||
Cardiovascular disease | 30,121 (15.5) | 28,326 (48.2) | 7573 (15.4) | 6823 (45.8) |
Inflammatory musculoskeletal condition | 28,002 (14.4) | 10,981 (18.7) | 14,905 (30.4) | 4984 (33.5) |
Inflammatory systemic disease | 2792 (1.4) | 1296 (2.2) | 1135 (2.3) | 462 (3.1) |
Pain and fever | 2410 (1.2) | 630 (1.1) | 1044 (2.1) | 259 (1.7) |
Cancer stagee (%) | ||||
Localized limited | 57,011 (29.4) | 14,106 (24.0) | 13,274 (27.1) | 3474 (23.3) |
Localized advanced | 11,719 (6.0) | 3906 (6.6) | 2328 (4.7) | 743 (5.0) |
Regional spread | 20,914 (10.8) | 5571 (9.5) | 4730 (9.6) | 1314 (8.8) |
Distant metastasis | 19,155 (9.9) | 6317 (10.8) | 5954 (12.1) | 1934 (13.0) |
Unknown | 72,027 (37.1) | 23,868 (40.6) | 18,232 (37.2) | 5929 (39.8) |
Not applicablef | 13,372 (6.9) | 4993 (8.5) | 4541 (9.3) | 1492 (10.0) |
Cancer typeg (%) | ||||
Prostate cancer | 37,380 (19.2) | 12,510 (21.3) | 9699 (19.8) | 3309 (22.2) |
Breast cancer | 30,135 (15.5) | 4702 (8.0) | 7484 (15.3) | 1313 (8.8) |
Gastrointestinal cancer | 34,625 (17.8) | 11,340 (19.3) | 7029 (14.3) | 2381 (16.0) |
Lung cancer | 11,126 (5.7) | 4612 (7.8) | 3867 (7.9) | 1426 (9.6) |
Non-melanoma skin cancer | 11,619 (6.0) | 5612 (9.6) | 2190 (4.5) | 1057 (7.1) |
Melanoma | 11,417 (5.9) | 2242 (3.8) | 2233 (4.6) | 547 (3.7) |
Kidney & bladder cancer | 10,785 (5.6) | 4764 (8.1) | 2735 (5.6) | 1155 (7.8) |
Gynecological cancer | 11,313 (5.8) | 2438 (4.1) | 2901 (5.9) | 615 (4.1) |
Hematological malignancy | 13,372 (6.9) | 4993 (8.5) | 4541 (9.3) | 1492 (10.0) |
Other cancers | 22,426 (11.5) | 5548 (9.4) | 6380 (13.0) | 1591 (10.7) |