Fig. 2

Treatment algorithm for blood glucose control in type 2 diabetes and treatment paths of the 10 pharmacologic combination strategies. Sulfonylurea includes glyburide, glimepiride, gliclazide, glipizide, and gliquidone. Thiazolidinedione includes rosiglitazone and pioglitazone. α-Glucosidase inhibitor includes acarbose, voglibose, and miglitol. Glinide includes repaglinide, nateglinide, and mitiglinide. DPP-4 inhibitor includes sitagliptin, saxagliptin, vildagliptin, linagliptin, and alogliptin. Insulin includes various kinds of insulin and insulin analogs. GLP-1 receptor agonist includes exenatide and liraglutide