Fig. 5

Forest plot of hazard ratios of 22 specific cancer sites related to a 1 standard deviation increase in body mass index and a 1 standard deviation increase in waist circumference. Notes: (1) SD for BMI and WC were 5.3 and 13.9 overall, 5.8 and 14.5 for women, 6.5 and 16.1 for pre-menopausal women, 5.4 and 13.3 for post-menopausal women, and 4.7 and 12.9 for men. (2) Separate models were fitted for each cancer type and adjusted for smoking status, alcohol intake, nationality, the MEDEA deprivation index, type 2 diabetes, and had sex and age (5-year categories) in the strata statement. (3) HRs are ordered by the descending ranking of BMI estimates from Fig. 4. (4) Brain and CNS include pituitary gland and pineal gland tumors. (5) Models for ovary, cervix, and corpus uteri cancers were only computed in women, for breast post-menopausal only in post-menopausal women, and for prostate only computed in men. (6) We only calculated hazard ratios for cancer types for which we ascertained at least 100 cancer cases. Abbreviations: BMI, body mass index; CI, confidence interval; CNS, central nervous system; SD, standard deviation; WC, waist circumference