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Table 2 Associations between maternal E-DII and DASH scores (per 1-SD increase) and secondary childhood adiposity measures

From: Maternal dietary quality, inflammatory potential and childhood adiposity: an individual participant data pooled analysis of seven European cohorts in the ALPHABET consortium

 

Early-childhood (2.8 ± 0.3 years)

Mid-childhood (6.1 ± 0.6 years)

Late-childhood (10.6 ± 1.2 years)

SST, mm

 

SST, mm

 

FMI, kg/m2

 

FFMI, kg/m2

 

SST, mm

 

FMI, kg/m2

 

FFMI, kg/m2

 

β (95% CI)

I2 (%)

β (95% CI)

I2 (%)

β (95% CI)

I2 (%)

β (95% CI)

I2 (%)

β (95% CI)

I2 (%)

β (95% CI)

I2 (%)

β (95% CI)

I2 (%)

E-DII

 Pre

− 0.11 (−0.23, 0.01)

0

− 0.04 (− 0.22, 0.14)

0

− 0.01 (− 0.04, 0.03)

0

− 0.04 (− 0.08, 0.003)

0

− 0.17 (− 0.76, 0.41)

–

0.03 (− 0.10, 0.16)

–

− 0.03 (−-0.10, 0.05)

–

 Np/Nc

2959/2

 

2536/2

 

2034/2

 

2038/2

 

1025/1

 

848/1

 

848/1

 

 Preg

− 0.01 (− 0.14, 0.13)

13

0.09 (− 0.14, 0.33)

29

0.03 (− 0.03, 0.09)

25

− 0.06 (− 0.16, 0.03)

67*

0.41 (− 0.23, 1.06)

–

0.03 (− 0.03, 0.10)

0

− 0.06 (− 0.08, − 0.03)***

0

 Np/Nc

2749/3

 

3184/4

 

2059/4

 

2063/4

 

780/1

 

6739/2

 

6739/2

 

 Early

0.07 (− 0.10, 0.24)

0

− 0.01 (− 0.28, 0.25)

0

0.01 (− 0.10, 0.13)

41

− 0.13 (− 0.32, 0.06)

77*

0.20 (− 0.43, 0.82)

–

0.04 (− 0.09, 0.17)

–

− 0.04 (− 0.12, 0.04)

–

 Np/Nc

1716/2

 

1513/2

 

1120/3

 

1119/3

 

836/1

 

702/1

 

702/1

 

 Late

− 0.04 (− 0.17, 0.08)

0

0.15 (− 0.07, 0.38)

17

0.03 (− 0.01, 0.07)

0

− 0.001 (− 0.04, 0.04)

0

0.31 (− 0.28, 0.90)

–

0.04 (− 0.03, 0.11)

12

− 0.04 (− 0.10, 0.01)

52

 Np/Nc

2880/2

 

3182/3

 

1980/2

 

1984/2

 

969/1

 

6885/2

 

6885/2

 

DASH

 Pre

− 0.03 (− 0.16, 0.09)

2

− 0.18 (− 0.36, 0.01)

0

− 0.04 (− 0.08, 0.003)

0

0.03 (− 0.01, 0.08)

0

− 0.29 (− 0.88, 0.31)

–

− 0.10 (− 0.23, 0.03)

–

0.05 (− 0.03, 0.12)

–

 Np/Nc

2959/2

 

2536/2

 

2034/2

 

2038/2

 

1025/1

 

848/1

 

848/1

 

 Preg

− 0.06 (− 0.18, 0.07)

0

− 0.02 (− 0.29, 0.26)

41

− 0.02 (− 0.05, 0.02)

0

0.01 (− 0.03, 0.06)

0

− 0.54 (− 1.21, 0.12)

–

− 0.09 (− 0.15, − 0.03)**

0

0.03 (− 0.002, 0.06)

0

 Np/Nc

2749/3

 

3184/4

 

2059/4

 

2063/4

 

780/1

 

6739/2

 

6739/2

 

 Early

− 0.10 (− 0.28, 0.08)

0

0.10 (− 0.41, 0.61)

68

− 0.07 (− 0.15, 0.01)

0

0.03 (− 0.03, 0.09)

0

− 0.58 (− 1.22, 0.06)

–

− 0.12 (− 0.25, 0.01)

–

0.06 (− 0.02, 0.14)

–

 Np/Nc

1716/2

 

1513/2

 

1120/3

 

1119/3

 

836/1

 

702/1

 

702/1

 

 Late

− 0.01 (− 0.14, 0.11)

0

− 0.06 (− 0.24, 0.13)

0

− 0.01 (− 0.05, 0.03)

0

− 0.001 (− 0.05, 0.04)

0

− 0.28 (− 0.88, 0.32)

–

− 0.07 (− 0.13, − 0.01)*

0

0.03 (− 0.002, 0.05)

0

 Np/Nc

2880/2

 

3182/3

 

1980/2

 

1984/2

 

969/1

 

6885/2

 

6885/2

 
  1. Values are adjusted pooled effect estimates [β (95% CI)] expressed for a 1-SD increment in dietary scores, heterogeneity measure (I2), and number of participants and studies included (Np/Nc) across different outcomes and conception periods, as labelled. Effect estimates were adjusted for maternal education, ethnicity, pre-pregnancy BMI, maternal height, parity, energy intake (for DASH analysis only), cigarette smoking and alcohol consumption during pregnancy and child sex and age at measurement
  2. β (effect estimates) and the I2 (heterogeneity) test have separate P values
  3. E-DII energy-adjusted Dietary Inflammatory Index, DASH Dietary Approaches to Stop Hypertension, SST sum of skinfold thickness, FMI fat mass index, FFMI fat-free mass index, I2 I-squared, Pre pre-pregnancy, Preg pregnancy, Early early pregnancy, Late late pregnancy, Np number of participants included, Nc number of cohorts included
  4. *P < 0.05, **P < 0.01, ***P < 0.001