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Table 3 A) distribution of HPV-RNA positivity over groups with cytology scores NILM and ASCUS+ (reason for referral to a gynecologist). B) distribution of HPV-RNA positivity in scrapes from women with an outcome <CIN2+ and >CIN2+ (median follow up 7 months)

From: Targeted RNA next generation sequencing analysis of cervical smears can predict the presence of hrHPV-induced cervical lesions

A

B

 

NILM

ASCUS+

sens: 83%

 

<CIN2

CIN2+

sens: 81%

hrHPVE6/7 neg

197

36

spec: 65%

hrHPVE6/7 neg

217

37

spec: 48%

hrHPVE6/7 pos

96

177

NPV=85%

hrHPVE6/7 pos

165

155

NPV=85%

   

PPV=66%

   

PPV=48%

   

sens:52%

   

sens:56%

hrHPVE6* neg

256

103

spec: 75%

hrHPVE6* neg

318

85

spec: 59%

hrHPVE6* pos

37

110

NPV:71%

hrHPVE6* pos

75

107

NPV:79%

   

PPV: 75%

   

PPV: 59%