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Table 2 Associations of aging makers with OA risk, NHANES 1999–2016

From: Biological aging mediates the associations between urinary metals and osteoarthritis among U.S. adults

 

Continuous

Q1

Q2

Q3

Q4

P for trend

 

OR (95% CI)

 

OR (95% CI)

OR (95% CI)

OR (95% CI)

 

Biological age

1.06 (1.05, 1.07)

1.00 (reference)

4.32 (1.90, 9.84)

15.1 (6.69, 34.07)

16.75 (7.46, 37.64)

 < 0.001

Phenotypic age

1.04 (1.04, 1.05)

1.00 (reference)

6.48 (2.74, 15.31)

18.78 (8.03, 43.93)

22.91 (9.31, 56.37)

 < 0.001

Telomere length

0.26 (0.07, 0.97)

1.00 (reference)

0.76 (0.37, 1.54)

0.58 (0.30, 1.11)

0.40 (0.17, 0.90)

0.022

  1. Models were adjusted for sex, age, race/ethnicity, education, family income-to-poverty ratio, marital status, body mass index, physical activity, drinking alcohol status, and serum cotinine. Q, quartile. All P for trend were FDR-adjusted
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BMC Medicine

ISSN: 1741-7015

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