Fig. 2

Adjusted HR (95% CI) of incident dementia for metabolites after multiple testing. Hazard ratios (HR) are per 1 standard deviation (SD) higher of Z-transformed metabolic marker and are adjusted for age, gender, education level, systolic pressure, anti-hypertension treatment, diabetes mellitus, smoking status, history of stroke, history of coronary heart disease, and APOE ε4 allele. CI, confidence interval; LDL, low-density lipoprotein; HDL, high-density lipoprotein; VLDL, very-low-density lipoprotein; IDL, intermediate-density lipoprotein