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Fig. 6 | BMC Medicine

Fig. 6

From: Integrated epigenome, whole genome sequence and metabolome analyses identify novel multi-omics pathways in type 2 diabetes: a Middle Eastern study

Fig. 6

Volcano plot showing the significant CpG-metabolite associations, indicating the gene and metabolite of the top 5 significant associations (top). Metabolic pathways associated with T2D CpGs, with significant associations are above the threshold red line (bottom). The top most significant associations are labelled 1–10 and they are all TXNIP associations with (1) 1,5 AG, (2) X – 24295, (3) pyruvate, (4) 2-methyl-2-oxobutyrate, (5) X – 24334, (6) mannonate, (7) glucose, (8) 1-palmitoyl-2-arachidonoyl-GPE (16:0/20:4), (9) 2-hydroxybutyrate/2-hydroxyisobutyrate, (10) alanine

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BMC Medicine

ISSN: 1741-7015

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