Fig. 2

Necrosis and granulation changes between and within groups received larvae or conventional therapy. Necrosis was significantly decreased in patients who received larvae on days 2 and 4 compared to baseline and conventional treatment groups. The larvae group had significantly improved granulation throughout the interventional duration. Error bars represent the standard deviation for the bar charts and the standard error of the mean for scatter plots. * shows statistical differences between groups, *P < 0.05, **P < 0.01, ***P < 0.001