Table 2 Associations between 1-point increment in total adherence score and risk of all cancers combined and of cancer at individual anatomical sites

All cancers combined

93,630

7296

0.92 (0.90; 0.94)

 < 0.001^a

0.93 (0.90; 0.95)

 < 0.001^a

Prostate

43,851

1818

1.01 (0.96; 1.05)

0.759

1.00 (0.96; 1.05)

0.959

Breast

50,337

1438

0.90 (0.85; 0.95)

 < 0.001^a

0.90 (0.86; 0.95)

 < 0.001^a

 Pre-menopausal

1108

154

0.83 (0.72; 0.96)

0.014

0.83 (0.72; 0.96)

0.013

 Post-menopausal

49,229

1284

0.90 (0.85; 0.95)

 < 0.001^a

0.90 (0.85; 0.95)

 < 0.001^a

Colorectal

94,656

863

0.89 (0.83; 0.95)

0.001^a

0.90 (0.84; 0.97)

0.003^a

 Colon

94,698

575

0.83 (0.76; 0.90)

 < 0.001^a

0.83 (0.77; 0.90)

 < 0.001^a

 Distal

94,734

242

0.74 (0.65; 0.84)

 < 0.001^a

0.75 (0.66; 0.85)

 < 0.001^a

 Proximal

94,748

303

0.89 (0.80; 1.00)

0.050

0.90 (0.81; 1.01)

0.074

 Rectum

94,734

342

1.00 (0.91; 1.12)

0.878

1.03 (0.93; 1.15)

0.588

Lung

94,760

431

0.86 (0.78; 0.94)

 < 0.001^a

0.93 (0.84; 1.02)

0.125

Kidney

94,754

221

0.82 (0.72; 0.93)

0.003^a

0.82 (0.72; 0.94)

0.004

Pancreas

94,770

213

0.87 (0.76; 0.99)

0.035

0.88 (0.77; 1.00)

0.056

Uterus

50,588

212

0.93 (0.81; 1.06)

0.269

0.92 (0.81; 1.05)

0.227

Oesophagus

94,765

151

0.81 (0.69; 0.95)

0.010

0.84 (0.71; 0.98)

0.031

Ovary

50,603

147

0.76 (0.65; 0.90)

0.001^a

0.76 (0.65; 0.90)

0.001^a

Bladder

94, 756

141

0.88 (0.74; 1.03)

0.116

0.90 (0.76; 1.07)

0.240

Head and neck

94,763

129

1.17 (0.99; 1.40)

0.068

1.21 (1.02; 1.44)

0.031

Stomach

94,770

99

0.97 (0.79; 1.18)

0.725

0.98 (0.80; 1.19)

0.830

Liver

94,773

82

0.77 (0.62; 0.96)

0.017

0.78 (0.63; 0.97)

0.024

Gallbladder

94,777

49

0.71 (0.54; 0.94)

0.017

0.70 (0.53; 0.93)

0.013