Fig. 7

Correlation between maternal metabolites and neurocognitive behavioral development later in life in offspring. A Bar plot showing the percentage of different classes of scores in sFGR and MCDA groups for each developmental domain of the Ages and Stages Questionnaires third edition subscale (ASQ-3). B The correlation between the four metabolite concentrations and five evaluation indices of neurocognitive behavioral development were examined by Spearman correlation analysis. Spearman’s correlation coefficients (R) were used to present the correlation. The shadow around the linear regression trendline shows the 95% confidence interval (CI). The metabolite level in B was determined as Log2-transformed metabolite concentrations (μM); sFGR, selective fetal growth restriction; MCDA, normal monochorionic diamniotic twins; P < 0.05 was considered statistically significant