Outcomes | Case definition | N | N cases | % cases |
---|---|---|---|---|
Binary outcomes | ||||
 Miscarriagea | Self-reported in index pregnancy | 91,757 | 107 | 0.12% |
Self-reported in previous pregnancies | 376,434 | 70,181 | 15.71% | |
 Stillbirtha | Self-reported in index pregnancy | 91,942 | 292 | 0.32% |
Self-reported in previous pregnancies | 174,440 | 4613 | 2.58% | |
 Hypertensive disorders of pregnancy | Gestational hypertension or preeclampsiab | 416,803 | 26,867 | 6.06% |
 Gestational hypertension | Elevated blood pressure without proteinuriab | 406,103 | 17,607 | 4.16% |
 Preeclampsia | Elevated blood pressure with proteinuriab | 401,184 | 9827 | 2.39% |
 Gestational diabetes | Hyperglycaemia first diagnosed in pregnancyc | 446,526 | 14,338 | 3.11% |
 Maternal anaemia | Maternal anaemia during pregnancy defined as Hb < 110 g/L (1st trimester) or Hb < 105 g/L(2nd or 3rd trimesters) | 92,002 | 2425 | 2.57% |
 Perinatal depression | Self-reported diagnosis or assessed depression symptom scales | 113,614 | 9320 | 7.58% |
 Pre-labour rupture of membranes* | Membrane rupture before the onset of contractions | 249,265 | 19,339 | 7.20% |
 Induction of labour* | Labour needed induction | 114,075 | 17,351 | 13.20% |
 Caesarean section* | Delivery by caesarean section | 204,093 | 27,967 | 12.05% |
 Preterm birth* | Gestational age at birth < 37 weeks | 261,473 | 14,090 | 5.11% |
 Large-for-gestational age* |  > 90th percentile for z-score of birthweight accounting for sex and gestational aged | 118,667 | 12,386 | 9.45% |
 Small-for-gestational age* |  < 10th percentile for z-score of birthweight accounting for sex and gestational aged | 118,667 | 8958 | 7.02% |
 Low birthweight* | Birthweight < 2500 g | 247,716 | 14,964 | 5.70% |
 High birthweight* | Birthweight ≥ 4000 g | 239,460 | 8142 | 3.29% |
 Low Apgar score at 1 min* | Apgar score at 1 min < 7 | 98,868 | 5760 | 5.51% |
 Low Apgar score at 5 min* | Apgar score at 5 min < 7 | 99,434 | 1167 | 1.16% |
 Neonatal intensive care unit (NICU) admission* | Neonate admitted to NICU | 93,522 | 8262 | 8.12% |
 Breastfeeding initiation* | Ever breastfed | 94,116 | 78,472 | 45.47% |
Continuous outcomes | ||||
 Birthweight* | NA | 326,537 | NA | NA |
 Birth length* | NA | 95,649 | NA | NA |
 Ponderal index at birth* | NA | 95,562 | NA | NA |
 Gestational age at birth* | NA | 118,723 | NA | NA |