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Fig. 3 | BMC Medicine

Fig. 3

From: Multiomics characterization of pyroptosis in the tumor microenvironment and therapeutic relevance in metastatic melanoma

Fig. 3

Pyroptosis is associated with cancer hallmark pathways and multiple cancer features. A Correlation of PScore with cancer hallmark pathways in multiple melanoma cohorts. The horizontal axis is the pathway names, and the vertical axis is the dataset identifiers. “TCGA_metastatic” refers to metastatic TCGA-SKCM patients. Red and blue denote high and low correlation coefficients, respectively. Significant points are labeled using black diamonds. B-D Correlation of PScore with DNA damage measures in metastatic melanoma. The x-axis is PScore, and the y-axis represents loss of heterozygosity (LOH), aneuploidy, and homologous recombination deficiency (HRD) from left to right. Each point represents a patient, and the blue line is the fitted correlation line. Log10(LOH_n_seg) denotes the LOH data were log10-transformed

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BMC Medicine

ISSN: 1741-7015

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