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Fig. 1 | BMC Medicine

Fig. 1

From: Genetically predicted plasma levels of amino acids and metabolic dysfunction-associated fatty liver disease risk: a Mendelian randomization study

Fig. 1

Schematic overview of the study design and MR analysis. a. rs3970551 was absent from the IV set in the replication MAFLD GWAS by Anstee et al. due to non-available proxy SNPs being identified. A The causal diagram of the relationship between circulating amino acids and MAFLD investigated in the two-sample MR analysis. B The data source of amino acids and MAFLD and relevant information on genetic instrumental variables selected as well as statistical analysis methods used in the study. GWAS, genome-wide association study; IV, instrumental variable; IVW, inverse variance weighted; MAFLD, metabolic dysfunction-associated fatty liver disease; MR, Mendelian randomization

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BMC Medicine

ISSN: 1741-7015

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