Clinical efficacy of sodium bicarbonate in treating pediatric metabolic acidosis with varying level of acid–base balance parameters: a real-world study

Table 3 Risk of mortality in overall children treated with sodium bicarbonate

Endpoint	Treatment	Death, n (%)		p	Crude	Adjusted^a	p
Endpoint	Treatment	No	Yes	p	OR (95% CI)	OR (95% CI)	p
Death in hospital	With SB	2230 (90.6)	232 (9.4)	0.616	0.956 (0.802, 1.140)	1.023 (0.826, 1.269)	0.833
Death in hospital	Without SB	3069 (90.2)	334 (9.8)		1	1
28-day death	With SB	2256 (91.6)	206 (8.4)	0.992	0.999 (0.828, 1.205)	1.096 (0.871, 1.378)	0.435
28-day death	Without SB	3118 (91.6)	285 (8.4)		1	1

Notation: SB Sodium bicarbonate, OR The odds ratio of death for children treated with SB as compared to those without
^aa binary logistic multivariate regression model using death as the dependent variable, adjusted for factors including age, sepsis, pneumonia, meningoencephalitis, surgery, disease diagnosis, HCO₃⁻, Ca²⁺, K⁺, Cl⁻, Na⁺, PaCO_2, lactate, total bilirubin, triglyceride, total protein, hemoglobin, red blood cell, white blood cell

ISSN: 1741-7015