Fig. 3

Association of hormone levels with vaginal microbiome. A Association of hormone level with the vaginal microbiome at different visits, all P values were adjusted by the Benjamini–Hochberg method. F and P values were inferred from the PERMANOVA analysis based on Bray–Curtis distance; B–D Network maps of the association of specific microbial genera and hormone level based on Spearman’s coefficients. Green circles indicate specific genera, orange circles indicate specific hormone indexes, and the circle diameter indicates relative abundance. Green lines indicate negative coefficients, red lines indicate positive coefficients, and line thickness indicates the coefficient value