Table 1 Comparison of characteristics of patients with intellectual disability disorders (IDDs) and non-IDDs group before and after matching
Before matching | After matching | |||||
|---|---|---|---|---|---|---|
IDD group (n = 18,154) | Non-IDD group (n = 5,260,322) | Std diff | IDD group (n = 18,148) | Non-IDD group (n = 18,148) | Std diff | |
Age at Index | 38.9 ± 17.0 | 46.3 ± 18.5 | 0.419 | 38.9 ± 17.0 | 39.8 ± 17.5 | 0.053 |
Sex | ||||||
Female | 9207 (50.72%) | 2918736 (55.49%) | 0.096 | 9204 (50.72%) | 8854 (48.79%) | 0.039 |
Male | 8945 (49.27%) | 2338751 (44.46%) | 0.097 | 8942 (49.27%) | 9285 (51.16%) | 0.038 |
Race | ||||||
White | 12198 (67.19%) | 2686343 (51.07%) | 0.332 | 12194 (67.19%) | 12377 (68.2%) | 0.022 |
Black or African American | 3591 (19.78%) | 686954 (13.06%) | 0.182 | 3589 (19.78%) | 3656 (20.15%) | 0.009 |
Asian | 344 (1.9%) | 111763 (2.13%) | 0.016 | 344 (1.9%) | 200 (1.1%) | 0.065 |
Unknown Race | 1933 (10.65%) | 1753455 (33.33%) | 0.569 | 1933 (10.65%) | 1880 (10.36%) | 0.010 |
Socioeconomic determinants of health | ||||||
Problems related to education and literacy | 79 (0.44%) | 2593 (0.05%) | 0.079 | 78 (0.43%) | 64 (0.35%) | 0.012 |
Problems related to employment and unemployment | 233 (1.28%) | 6852 (0.13%) | 0.138 | 231 (1.27%) | 188 (1.04%) | 0.022 |
Problems related to housing and economic circumstances | 729 (4.02%) | 18641 (0.35%) | 0.252 | 727 (4.01%) | 752 (4.14%) | 0.007 |
Comorbidities | ||||||
Hypertensive diseases | 3835 (21.13%) | 651949 (12.39%) | 0.235 | 3831 (21.11%) | 4021 (22.16%) | 0.025 |
Overweight and obesity | 2961 (16.31%) | 288719 (5.49%) | 0.353 | 2956 (16.29%) | 2972 (16.38%) | 0.002 |
Type 2 diabetes mellitus | 2390 (13.17%) | 271320 (5.16%) | 0.280 | 2385 (13.14%) | 2407 (13.26%) | 0.004 |
Ischemic heart diseases | 687 (3.78%) | 158517 (3.01%) | 0.043 | 682 (3.76%) | 970 (5.35%) | 0.076 |
Cerebral infarction | 765 (4.21%) | 45595 (0.87%) | 0.214 | 760 (4.19%) | 703 (3.87%) | 0.016 |
Neoplasms | 2346 (12.92%) | 438104 (8.33%) | 0.150 | 2342 (12.91%) | 2282 (12.57%) | 0.010 |
Nicotine dependence | 1723 (9.49%) | 205371 (3.9%) | 0.225 | 1719 (9.47%) | 1659 (9.14%) | 0.011 |
Mood disorders | 2787 (15.35%) | 166147 (3.16%) | 0.430 | 2781 (15.32%) | 2963 (16.33%) | 0.027 |
Schizophrenia and other non-mood psychotic disorders | 1331 (7.33%) | 23571 (0.45%) | 0.362 | 1325 (7.3%) | 1352 (7.45%) | 0.006 |
Mental and behavioral disorders due to psychoactive substance use | 2344 (12.91%) | 280762 (5.34%) | 0.265 | 2338 (12.88%) | 2299 (12.67%) | 0.006 |
Chronic kidney disease | ||||||
Chronic kidney disease | 912 (5.02%) | 114238 (2.17%) | 0.154 | 912 (5.03%) | 1016 (5.6%) | 0.026 |
Hypertensive chronic kidney disease | 258 (1.42%) | 35244 (0.67%) | 0.074 | 258 (1.42%) | 273 (1.5%) | 0.007 |
Chronic liver diseases | ||||||
Fatty liver | 301 (1.66%) | 42123 (0.8%) | 0.078 | 301 (1.66%) | 353 (1.95%) | 0.022 |
Fibrosis and cirrhosis of liver | 150 (0.83%) | 18692 (0.36%) | 0.061 | 149 (0.82%) | 151 (0.83%) | 0.001 |
Alcoholic liver disease | 17 (0.09%) | 7917 (0.15%) | 0.016 | 17 (0.09%) | 66 (0.36%) | 0.057 |
Chronic hepatitis | 12 (0.07%) | 1307 (0.03%) | 0.019 | 12 (0.07%) | 15 (0.08%) | 0.006 |
Portal hypertension | 31 (0.17%) | 6199 (0.12%) | 0.014 | 31 (0.17%) | 47 (0.26%) | 0.019 |
Chronic lower respiratory diseases | ||||||
Chronic obstructive pulmonary disease | 361 (1.99%) | 65012 (1.24%) | 0.060 | 361 (1.99%) | 489 (2.7%) | 0.047 |
Asthma | 1870 (10.3%) | 166430 (3.16%) | 0.288 | 1865 (10.28%) | 1885 (10.39%) | 0.004 |
Bronchitis | 299 (1.65%) | 42117 (0.8%) | 0.077 | 299 (1.65%) | 359 (1.98%) | 0.025 |
Simple and mucopurulent chronic bronchitis | 25 (0.14%) | 3998 (0.08%) | 0.019 | 25 (0.14%) | 19 (0.11%) | 0.010 |
Emphysema | 87 (0.48%) | 21164 (0.4%) | 0.012 | 84 (0.46%) | 122 (0.67%) | 0.028 |
Dementia | ||||||
Vascular dementia | 20 (0.11%) | 1536 (0.03%) | 0.031 | 20 (0.11%) | 15 (0.08%) | 0.009 |
Alzheimer’s disease | 39 (0.22%) | 2903 (0.06%) | 0.043 | 38 (0.21%) | 26 (0.14%) | 0.016 |
Immune disorders | ||||||
Human immunodeficiency virus disease | 506 (2.79%) | 17105 (0.33%) | 0.200 | 502 (2.77%) | 395 (2.18%) | 0.038 |
Sarcoidosis | 24 (0.13%) | 6144 (0.12%) | 0.004 | 23 (0.13%) | 33 (0.18%) | 0.014 |
Immunodeficiency with predominantly antibody defects | 37 (0.2%) | 2631 (0.05%) | 0.043 | 37 (0.2%) | 16 (0.09%) | 0.030 |
Psoriasis | 211 (1.16%) | 25074 (0.48%) | 0.076 | 208 (1.15%) | 174 (0.96%) | 0.018 |
Rheumatoid arthritis | 134 (0.74%) | 24663 (0.47%) | 0.035 | 132 (0.73%) | 153 (0.84%) | 0.013 |
Systemic lupus erythematosus | 44 (0.24%) | 8076 (0.15%) | 0.020 | 43 (0.24%) | 73 (0.4%) | 0.029 |