Comparison of two single-pill dual combination antihypertensive therapies in Chinese patients: a randomized, controlled trial

Table 4 Number and incidence rate of adverse events

Adverse event	Amlodipine/benazepril (n = 282)	Benazepril/hydrochlorothiazide (n = 278)	p value
Dizziness	39 (13.8%)	34 (12.2%)	0.57
Hyperuricemia	33 (11.7%)	45 (16.2%)	0.13
Hypokalemia	32 (11.4%)	35 (12.6%)	0.65
Dry cough	15 (5.3%)	28 (10.1%)	0.04
Elevation of alanine or aspartate transaminase	1 (0.4%)	2 (0.7%)	0.55
Ankle edema	1 (0.4%)	0 (0)	0.32
Palpitation	1 (0.4%)	0 (0)	0.32
Stomachache	1 (0.4%)	0 (0)	0.32
Hypotension	1 (0.4%)	0 (0)	0.32
Skin rash	0 (0)	1 (0.4%)	0.31
Hair loss	0 (0)	1 (0.4%)	0.31
Total number of patients with at least one adverse event	109 (38.7%)	124 (44.6%)	0.15

Values are number of patients (% of column total), listed in the descending order of the incidence rate in the amlodipine/benazepril group and then the benazepril/hydrochlorothiazide group

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