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Table 1 Characteristics of the study population

From: Impact of preconception and antenatal supplementation with myo-inositol, probiotics, and micronutrients on offspring BMI and weight gain over the first 2 years

 

Intervention (n = 287)

Control (n = 289)

Study site

 UK

95 (33.1%)

92 (31.8%)

 Singapore

83 (28.9%)

82 (28.4%)

 New Zealand

109 (38.0%)

115 (39.8%)

Maternal ethnicitya

 White Caucasian

174 (60.6%)

167 (57.8%)

 Chinese

70 (24.4%)

73 (25.3%)

 South Asian

16 (5.6%)

15 (5.2%)

 Malay

11 (3.8%)

12 (4.2%)

 Others

16 (5.6%)

22 (7.6%)

Maternal BMI (kg/m2)

24.5 ± 5.1

25.1 ± 5.8

Maternal height (cm)

164.6 ± 6.6

163.7 ± 7.0

Parityb

 Nulliparous

166 (57.8%)

201 (69.6%)

 Multiparous

121 (42.2%)

88 (30.4%)

Maternal smoking during pregnancy

 None

256 (89.2%)

234 (81.0%)

 Passive smoking

22 (7.7%)

45 (15.6%)

 Active smoking

9 (3.1%)

10 (3.4%)

Household income quintile

 5 (lowest)

2 (0.4%)

5 (0.9%)

 4

21 (3.7%)

21 (3.7%)

 3

54 (9.4%)

68 (11.8%)

 2

107 (18.6%)

95 (16.5%)

 1 (highest)

92 (16.0%)

90 (15.6%)

 Not available

11 (1.9%)

10 (1.7%)

Infant sex

 Male

138 (48.1%)

130 (45.0%)

 Female

149 (51.9%)

159 (55.0%)

Gestational age (weeks)c

39.3 ± 1.5

39.2 ± 1.7

 Preterm

15 (5.2%)

27 (9.3%)

 Term

269 (93.7%)

260 (90.3%)

 Post-term

3 (1.0%)

2 (0.7%)

Birthweight (g)

3354 ± 524

3300 ± 542

Birthweight SDSd

0.00 ± 0.92

 − 0.04 ± 0.93

 SGA

22 (7.7%)

21 (7.3%)

 AGA

244 (85.0%)

246 (85.1%)

 LGA

21 (7.3%)

22 (7.6%)

Any breastfeeding

 Yes

273 (96.5%)

275 (98.6%)

 No

10 (3.5%)

4 (1.4%)

 Missing

4

10

Never exclusively breastfede

 Yes

162 (57.5%)

150 (54.4%)

 No

120 (42.6%)

126 (45.7%)

 Missing

5

13

Exclusive breastfeeding duration (weeks)e,f

7.7 ± 9.8

7.1 ± 9.7

 Missing

5

13

Any breastfeeding duration (weeks)f

38.6 ± 18.2

36.1 ± 19.9

 Missing

5

10

  1. Abbreviations: AGA Appropriate-for-gestational-age, BMI Body mass index, LGA Large-for-gestational-age, SDS Standard deviation score, SGA Small-for-gestational-age
  2. Data are mean ± SD or n (%)
  3. aSouth Asian includes Indian, Pakistani, and Bangladeshi mothers. “Others” includes mothers of mixed, Black, or Polynesian ethnicity
  4. bMultiparous includes mothers with one or more births > 24 weeks of gestation
  5. cPreterm defined as birth prior to 370/7 weeks of completed gestation, term as birth between 370/7 and 416/7 weeks of completed gestation, and post-term as birth at or beyond 420/7 weeks of completed gestation
  6. dCalculated using the UK–WHO reference [33]; SGA defined as below the 10th percentile (− 1.282 SD) and LGA as above the 90th percentile (1.282 SD)
  7. eExclusive breastfeeding defined as the infant having never received any water, formula, or other liquid or solid food, except for oral rehydration solution or drops/syrups of vitamins, minerals, or medicines
  8. fThose who were never breastfed or never exclusively breastfed were assigned a value of 0