Fig. 2

Correlations between eCBs and Trp to Kyn biomarkers in individuals with A the absence of depressive symptoms (MADRS score ≤ 6) and B the presence of mild to severe depressive symptoms (MADRS score > 6). Correlation scores are corrected for sex, age, and BMI. The legend on the right displays the color-coding of the correlations’ r values, with blue colors indicating a positive correlation (r > 0) and red colors indicating a negative correlation (r < 0). Asterisks within the circles represent significant correlations at *alpha level = 0.05, **alpha level = 0.01, and ***alpha level = 0.001 after the false discovery rate (FDR) control procedure