Skip to main content

Table 2 Demographic and clinical characteristics of individuals with absence (MADRS score ≤ 6) or mild to severe (MADRS score > 6) depressive symptoms according to the MADRS scale

From: Dysfunction in endocannabinoids, palmitoylethanolamide, and degradation of tryptophan into kynurenine in individuals with depressive symptoms

 

Individuals with absence of depressive symptoms (n = 33)

Individuals with mild to severe depressive symptoms (n = 49)

Statistics

Age, years

33.9 ± 13.8

41.7 ± 14.5

t = 2.406; df = 80; p = 0.018

Sex, m/f (%)

17 f (52)

16 m (48)

25 f (51)

24 m (49)

χ2 = 0.00, p = 1.00

BMI, kg/m2

23.5 ± 3.8

27.9 ± 6.5

t = 3.404; df = 80; p = 0.001

Total MADRS

2.1 ± 1.9

22.5 ± 8.7

t = 12.667; df = 80; p < 0.001

Total CGI-severity of illness

1.1 ± 0.4

3.9 ± 1.2

t = 12.428; df = 80; p < 0.001

Total BDI-II

3.2 ± 3.7

26.2 ± 14.7

t = 8.646; df = 80; p < 0.001

Diagnosis, n (%)

  

χ2= 78.05, p < 0.001

 Unipolar depression

1 (3)

34 (69)###

 

 Bipolar depression

1 (3)

15 (31)##

 

Pharmacotherapy, n (%)

  

χ2 = 74.01, p < 0.001

 Antidepressant

0 (0)

17 (35)###

 

 Antidepressant + antipsychotic

0 (0)

10 (20)#

 

 Antidepressant + antipsychotic + mood stabilizer

0 (0)

12 (25)###

 

 Antidepressant + mood stabilizers

0 (0)

2 (4)

 

 Antipsychotic + mood stabilizer

2 (6)

8 (16)

 

Marital status, n (%)

  

χ2 = 1.834, p = 0.766

 Single

19 (58)

29 (59)

 

 Engaged

1 (3)

1 (2)

 

 Married

6 (18)

10 (20)

 

 Common law

4 (12)

3 (6)

 

 Divorced/separated

3 (9)

6 (13)

 

Employment, n (%)

  

χ2 = 17.813, p = 0.001

 Unemployed

7 (21)

18 (37)

 

 Employed

16 (49)

18 (37)

 

 Disability/sick leave

0 (0)

10 (20)##

 

 Student

9 (27)

2 (4)##

 

 Welfare

1 (3)

1 (2)

 

Anxiety disorders, n (%)

0 (0)

23 (47)

χ2 = 20.458, p < 0.001

Personality disorders, n (%)

1 (3)

24 (49)

χ2 = 18.541, p < 0.001

  1. Comparisons were computed using the Student T test for continuous variables and Pearson’s chi-square (χ2) for categorical variables
  2. m males, f females, BMI body mass index, MADRS Montgomery Asberg Depression Rating Scale, CGI Clinical Global Impression, BDI-II Beck Depression Inventory version-II
  3. #p < 0.05, ##p < 0.01, ###p < 0.001 Pearson’s chi-square