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Table 1 Eligibility criteria for study selection

From: Proteomics for heart failure risk stratification: a systematic review

Category

Inclusion criteria

Exclusion criteria

Population

• Human

• Adults (aged ≥ 18 years) with HF irrespective of EF

• Non-human studies

• Children and adolescents (aged 2–17 years)

• Adults without HF

Measurement(s)/exposure(s)

• Assessed the plasma or serum proteome

• Proteins measured by high-throughput affinity-based proteomic techniques including aptamer-based (SomaScan) or antibody-based (Olink)

• Assessed biological proteome other than plasma or serum

• Proteomic techniques other than the large-scale affinity platforms

Comparator/association(s)

• Reported protein association with outcomes

• No protein association with outcomes reported

Outcome(s)

• All-cause death

• Cardiovascular death

• A composite outcome that includes death

• Absence of death outcomes

Study design(s)

• Observational studies (all types, e.g., cohort, case–control, cross-sections, longitudinal, prospective, retrospective)

• Clinical trials

• Articles without primary data (commentaries, editorials, protocols, letters, reviews of all types)

• Incomplete data (conference abstracts/proceedings)

Language

• No restrictions

• NA

Date of publication

• 2012 to June 2023

• Before 2012

  1. HF Heart failure, EF Ejection fraction