Table 4 Associations of obesity, sarcopenia, and sarcopenic obesity with brain structure for women and men
|  | β coefficients and 95% CIs in volume of different brain regions | ||||
|---|---|---|---|---|---|
| Â | Total brain * | White matter * | Grey matter * | Grey matter in hippocampus | White matter hyperintensities# |
Women (n = 6328) | Â | Â | Â | Â | Â |
 Normal | Ref | Ref | Ref | Ref | Ref |
 Obesity | 6751 (2549, 10953) | 8238 (5362, 11114) | − 1486 (− 4026, 1053) | − 39 (− 90, 13) | 0.05 (− 0.02, 0.11) |
 Sarcopenia | − 3229 (− 8677, 2220) | − 1849 (− 5568, 1871) | − 1380 (− 4693, 1933) | − 145 (− 212, − 78) | 0.06 (− 0.02, 0.14) |
 Sarcopenic obesity | 3429 (− 8426, 15284) | 6675 (− 1440, 14789) | − 3246 (− 10412, 3919) | − 108 (− 254, 38) | 0.16 (− 0.02, 0.34) |
Men (n = 7348) | Â | Â | Â | Â | Â |
 Normal | Ref | Ref | Ref | Ref | Ref |
 Obesity | − 12677 (− 16464, − 8891) | 2172 (− 428, 4771) | − 14850 (− 17170, − 12528) | − 21 (− 71, 28) | 0.25 (0.19, 0.31) |
 Sarcopenia | − 2536 (− 9963, 4892) | 1696 (− 3412, 6804) | − 4232 (− 8779, 316) | − 108 (− 205, − 12) | 0.05 (− 0.06, 0.17) |
 Sarcopenic obesity | − 11221 (− 25357, 2915) | 3423 (− 6281, 13127) | − 14640 (− 23309, − 5978) | − 174 (− 358, 10) | 0.26 (0.05, 0.48) |